Stresses which arise in bioreactors can influence process performance considerably. Recent molecular biological investigations indicate that stress caused by fluid dynamical effects and extreme values of process variables and toxic substances cause similar responses in the cells. These molecular fundamentals, as well as quantitative evaluation of fluid dynamical stresses and, their effects on microorganisms, animal and plant cells and proteins are treated in this volume.

Inhalt

Function and Regulation of Temperature-Inducible Bacterial Proteins on the Cellular Metabolism.- Particle Stress in Bioreactors.- The Engineering Effects of Fluids Flow on Freely Suspended Biological Macro-Materials and Macromolecules.- Influence of Stress on Adherent Cells.- Effects of Hydrodynamic and Interfacial Forces on Plant Cell Suspension Systems.