This book aims to introduce the latest research in gut microbiota by systematically summarizing how it modulates the pathogenesis of organ injury including alimentary tract injury, liver injury, lung injury, brain injury, renal injury, heart and vascular injury, endocrine disorders, immune responses and multiple organ dysfunction syndrome (MODS) during sepsis. Gut microbiota which is recognized as a new "organ" in the body has been demonstrated to be able to regulate the homeostasis of many organs. The key role played by gut microbiota is the hotspot in biomedical research nowadays. This book provides a state-of-the-art report on recent discoveries regarding the novel insight into the mechanisms of human diseases progression. It will also offer the overall picture of the pathophysiologic roles of gut microbiota. This book is helpful for graduate students and professional researchers to get the knowledge of frontiers in both gut microbiota and organ injury.

Autorentext

Dr. Peng Chen is a professor from Department of Pathophysiology, Southern Medical University, China. He is the youth committee member of Chinese Association of Pathophysiology (CAOP), and youth committee member of receptor branch of CAOP. He is also the Youth Pearl River Scholar entitled by Guangdong province, China. Prof. Chen's research focuses on gut microbiota. As first or corresponding author, he has published several articles on international journals in this field, including Gastroenterology, J Hepatol, Hepatology, FASEB J and Am J Pathol.

Inhalt
Introduction.- Gut microbiota and alimentary tract injury.- Gut microbiota and liver injury - Acute liver injury.- Gut microbiota and liver injury - Chronic liver injury.- Gut microbiota and lung injury.- Gut microbiota and brain injury.- Gut microbiota and renal injury.- Gut microbiota and heart, vascular injury.- Gut microbiota and endocrine disorders.- Gut microbiota and immune responses.- Gut microbiota and multiple organ dysfunction syndrome (MODS).