J. Warren Evans Department of Animal Science Texas A&M University College Station, Texas 77843 In the near future, improvement of domestic animals for the production of food and fiber is poised to undergo a revolution by the utilization of recent breakthroughs and advances in molecular genetics, embryo manipula­ tions, and gene transfer systems. Utilization of these techniques will have a wide impact on animal agriculture by improvement of production effi­ ciency via manipulation and control of many physiological systems. The end result will be to decrease production costs, increase food production and quality, and lower food costs. Health and well being of domestic and other animals will be improved as a result of new methods of disease diagnosis, vaccine production, and disease prevention practices. Genetic engineering also offers the possibility of utilizing animals for the development of pharmaceutical products to benefit society. Research progress will be en­ hanced via manipulation of the gene pool. The objectives of this Conference were to discuss the current status of animal bioengineering and to realistically assess the potential applica­ tions of current and future genetic technologies for the production of food and fiber to meet the needs of our hungry world, and to provide animal sci­ entists who may wish to utilize bioengineering in current or future re­ search programs with current background information regarding concepts, ap­ plications, and methodologies.

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Welcome: Challenges Encountered by the College of Agricultural and Environmental Sciences.- Concepts In Genetic Engineering.- Genetic Engineering of Animals.- Manipulation of Genes In Vitro and In Vivo.- Expression of the Bovine Growth Hormone Gene in Cultured Rodent Cells.- Sources Of Genetic Material.- Mapping Genes in Domesticated Animals.- Gene Transfer into Animals by Retroviral Vectors.- Booroola (F) Gene: Major Gene Affecting Ovine Ovarian Function.- Casein Genes and Genetic Engineering of the Caseins.- Avian Hormones.- Applications In Laboratory And Domestic Animals: Overview And History.- History of Genetic Engineering of Laboratory and Farm Animals.- Genetic Analysis in Mammals: Past, Present, and Future.- and Regulation of Cloned Genes for Agricultural Livestock Improvement.- A Technique for Bisection of Embryos to Produce Identical Twins.- Production of Experimental Chimeras in Livestock by Blastocyst Injection.- Gene Transfer by Direct Pronuclei Microinjection.- Applications In Laboratory And Domestic Animals: Disease Aspects.- Application of Bioengineering to Disease Diagnosis.- Recombinant DNA Approaches to Feline Leukemia Virus Immunization.- Molecular Approaches to Vaccines.- Embryo Manipulation Identification of Sex in Mammalian Embryos.- Cryobiology: Preservation of Mammalian Embryos.- Legal, Regulatory, And Ethical Considerations.- Legal and Regulatory Aspects of Genetically Engineered Animals.- "The Frankenstein Thing": The Moral Impact of Genetic Engineering of Agricultural Animals on Society and Future Science.- Future Applications.- Characteristics of Future Agricultural Animals.- Where Does Genetic Engineering Lead?.- Roster of Speakers, Scientific Organizing Committee, Local Organizing Committee, and Participants.