Inhalt

The Regulation of the Glutathione.- Level in the Liver.- Turnover of Glutathione in Rat Liver.- Regulation of the Hepatic Concentration of Reduced Glutathione.- The Role of the Cystathionine Pathway in Glutathione Regulation by Isolated Hepatocytes.- Physiological Significance of Elevation of Liver ?-Glutamyltranspeptidase in Late Pregnancy.- Glutathione Efflux from Perfused Rat Liver and Its Relation to Glutathione Uptake by the Kidney.- Unidirectional Transport of Reduced Glutathione in Rat Liver and Its Metabolization in the Extracellular Space.- The Role of ?-Glutamyl-Transferase in Glutathione Turnover.- Current Status of the ?-Glutamyl Cycle.- Topology and Function of Renal ?-Glutamyl Transpeptidase.- The Membrane Association and Physiological Function of Rat Renal ?-Glutamyltranspeptidase.- Studies on the Active Site of ?-Glutamyl-transferase.- The Role of Glutathione in Transport Activity in Kidney.- Hydroperoxide and Disulfide Metabolism.- Hydroperoxide Metabolism: An Overview.- The Selenium Moiety of Glutathione Peroxidase.- Non-Selenium-Dependent Glutathione Peroxidase.- Properties of Glutathione Disulfide (GSSG) and Glutathione-SS-Conjugate Release from Perfused Rat Liver.- Reduction of Diazenes and Hydroperoxides by Rat Liver Mitochondria.- Effect of Oxidation of Glutathione and Membrane Thiol Groups on Mitochondrial Functions.- The Roles of Glutathione, Thioltransferase, and Glutathione Reductase in the Scission of Sulfur-Sulfur Bonds.- Pharmacological and Toxicological Aspects.- The Glutathione Transferases in Detoxification.- Functions of Glutathione in Drug Metabolism.- Lipid Peroxidation Induced by Ethanol and Halogenated Hydrocarbons in vivo as Measured by Ethane Exhalation.- Drug-induced Lipid Peroxidation in Mouse Liver.- Cellular Functions in Glutathione-Depleted Hepatocytes.- Glutathione and Glutathione Conjugate Metabolism in Isolated Liver and Kidney Cells.- Glutathione-Requiring Enzymes in the Metabolism of Prostaglandin Endoperoxides.