This book constitutes the refereed proceedings of the 4th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2007, held in Salt Lake City, UT, USA in June 2007. The contributions describe both experimental and computational studies and cover topics such as imaging and image analysis, cardiac electrophysiology, electro- and magnetocardiography, cardiac mechanics and clinical application, imaging and anatomical modeling.

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Imaging and Image Analysis.- Local Wall-Motion Classification in Echocardiograms Using Shape Models and Orthomax Rotations.- A Fully 3D System for Cardiac Wall Deformation Analysis in MRI Data.- Automated Tag Tracking Using Gabor Filter Bank, Robust Point Matching, and Deformable Models.- Strain Measurement in the Left Ventricle During Systole with Deformable Image Registration.- Vessel Enhancement in 2D Angiographic Images.- Effect of Noise and Slice Profile on Strain Quantifications of Strain Encoding (SENC) MRI.- Reconstruction of Detailed Left Ventricle Motion from tMRI Using Deformable Models.- Computer Aided Reconstruction and Motion Analysis of 3D Mitral Annulus.- Volumetric Analysis of the Heart Using Echocardiography.- Constrained Reconstruction of Sparse Cardiac MR DTI Data.- An Experimental Framework to Validate 3D Models of Cardiac Electrophysiology Via Optical Imaging and MRI.- A Framework for Analyzing Confocal Images of Transversal Tubules in Cardiomyocytes.- Cardiac Electrophysiology.- Computer Simulation of Altered Sodium Channel Gating in Rabbit and HumanVentricular Myocytes.- Scroll Waves in 3D Virtual Human Atria: A Computational Study.- Determining Recovery Times from Transmembrane Action Potentials and Unipolar Electrograms in Normal Heart Tissue.- Simulations of Cardiac Electrophysiological Activities Using a Heart-Torso Model.- An Anisotropic Multi-front Fast Marching Method for Real-Time Simulation of Cardiac Electrophysiology.- Parallel Solution in Simulation of Cardiac Excitation Anisotropic Propagation.- A Three Dimensional Ventricular E-Cell (3Dv E-Cell) with Stochastic Intracellular Ca 2?+? Handling.- A Model for Simulation of Infant Cardiovascular Response to Orthostatic Stress.- Effects of Geometry and Architecture on Re-entrant Scroll Wave Dynamics in Human Virtual Ventricular Tissues.- Can We Trust the Transgenic Mouse? Insights from Computer Simulations.- Relating Discontinuous Cardiac Electrical Activity to Mesoscale Tissue Structures: Detailed Image Based Modeling.- Electro- and Magetocardiography.- Is There Any Place for Magnetocardiographic Imaging in the Era of Robotic Ablation of Cardiac Arrhythmias?.- Towards the Numerical Simulation of Electrocardiograms.- Experimental Measures of the Minimum Time Derivative of the Extracellular Potentials as an Index of Electrical Activity During Metabolic and Hypoxic Stress.- Experimental Epicardial Potential Mapping in Mouse Ventricles: Effects of Fiber Architecture.- Noninvasive Electroardiographic Imaging: Application of Hybrid Methods for Solving the Electrocardiography Inverse Problem.- Towards Noninvasive 3D Imaging of Cardiac Arrhythmias.- Forward and Inverse Solutions of Electrocardiography Problem Using an Adaptive BEM Method.- Contributions of the 12 Segments of Left Ventricular Myocardium to the Body Surface Potentials.- Numerical Analysis of the Resolution of Surface Electrocardiographic Lead Systems.- Simultaneous High-Resolution Electrical Imaging of Endocardial, Epicardial and Torso-Tank Surfaces Under Varying Cardiac Metabolic Load and Coronary Flow.- Cardiac Mechanics and Clinical Application.- Characteristic Strain Pattern of Moderately Ischemic Myocardium Investigated in a Finite Element Simulation Model.- Constitutive Modeling of Cardiac Tissue Growth.- Effect of Pacing Site and Infarct Location on Regional Mechanics and Global Hemodynamics in a Model Based Study of Heart Failure.- Effective Estimation in Cardiac Modelling.- Open-Source Environment for Interactive Finite Element Modeling of Optimal ICD Electrode Placement.- Mathematical Modeling of Electromechanical Function Disturbances and Recovery in Calcium-Overloaded Cardiomyocytes.- Locally Adapted Spatio-temporal Deformation Model for Dense Motion Estimation in Periodic Cardiac Image Sequences.- Imaging and Anatomical Modeling.- Visualisation of Dog Myocardial Structure from Diffusion Tensor Magnetic Resonance Imaging: The Paradox of Uniformity and Variability.- Statistical Comparison of Cardiac Fibre Architectures.- Extraction of the Coronary Artery Tree in Cardiac Computer Tomographic Images Using Morphological Operators.- Segmentation of Myocardial Regions in Echocardiography Using the Statistics of the Radio-Frequency Signal.- A Hyperelastic Deformable Template for Cardiac Segmentation in MRI.- Automated Segmentation of the Left Ventricle Including Papillary Muscles in Cardiac Magnetic Resonance Images.- Simulation of 3D Ultrasound with a Realistic Electro-mechanical Model of the Heart.- Automated, Accurate and Fast Segmentation of 4D Cardiac MR Images.