The research and outcomes presented in this book gather evidence concerning both the pathogenesis and treatment of functional dyspepsia. It provides the latest information on this common non-organic disease, indicating its characteristic pathogenesis based on the brain-gut interaction and micro-environment and evidence gleaned from clinical treatment. Since the pathogenesis is associated with psychology, neurology, endocrinology and bacteriology in addition to gastroenterological physiology, it is often intractable and finding a suitable treatment rationale is challenging. Furthermore, the pathogenesis varies around the world and the efficacy of treatment using standard drugs varies among different populations worldwide; accordingly, this book highlights evidence gained in clinical trials in Japan. Functional Dyspepsia is a milestone produced by respected experts. Addressing unique topics and new findings of treatment including challenging and/or future rationales, it offers an invaluable resource for general clinicians, gastroenterologists, and basic researchers alike.

Autorentext
Kazunari Tominaga, Osaka Medical College, Second Department of Internal Medicine, Takatsuki, Japan
Hiroaki Kusunoki, Kawasaki Medical School, Department of General Medicine, Kurashiki, Japan

Inhalt
PART I: Etiology.-Chapter 1: Definition & Prevalence.-Chapter 2: Genetic Factor.-Chapter 3: Environmental Factors.-
PART II: Pathophysiology.-Chapter 4: Neuro-gastroenterology: Central & Autonomic Nervous System.-Chapter 5: Neuro-gastroenterology: Enteric Nervous System.-Chapter 6: Neuro-gastroenterology: Esophago-gastric Function (Motility) .-Chapter 7: Neuro-Gastroenterology: Gastro-duodenal Function (Motility) and Ultrasonographic Assessment.-Chapter 8: Ghrelin and Functional Dyspepsia.-Chapter 9: Psycho-gastroenterology.-Chapter 10: Visceral Hypersensitivity Through Transient Receptor Potential Vanilloid 1 Channels (TRPV1) in Functional Dyspepsia.-
PART III: Treatment.-Chapter 11: Efficacy of Acid Suppression Therapy.-Chapter 12: Prokinetics.-Chapter 13: Herbal Medicine.-
PART IV: Recent Special Topics: Future Treatment Possibility.-Chapter 14: Gut Dysbiosis and Its Treatment in Patients with Functional Dyspepsia.-Chapter 15: Visceral Hypersensitivity in Functional Dyspepsia (FD) - Therapeutic Approaches to FD Based on Suppression of Visceral Hypersensitivity.-Chapter 16: Pancreatic Exocrine Function.