Willkommen, schön sind Sie da!
Logo Ex Libris

Frontiers of Biostatistical Methods and Applications in Clinical Oncology

  • E-Book (pdf)
  • 438 Seiten
(0) Erste Bewertung abgeben
Bewertungen
(0)
(0)
(0)
(0)
(0)
Alle Bewertungen ansehen
This book presents the state of the art of biostatistical methods and their applications in clinical oncology. Many methodologies ... Weiterlesen
E-Books ganz einfach mit der kostenlosen Ex Libris-Reader-App lesen. Hier erhalten Sie Ihren Download-Link.
CHF 130.90
Download steht sofort bereit
Informationen zu E-Books
E-Books eignen sich auch für mobile Geräte (sehen Sie dazu die Anleitungen).
E-Books von Ex Libris sind mit Adobe DRM kopiergeschützt: Erfahren Sie mehr.
Weitere Informationen finden Sie hier.
Bestellung & Lieferung in eine Filiale möglich

Beschreibung

This book presents the state of the art of biostatistical methods and their applications in clinical oncology. Many methodologies established today in biostatistics have been brought about through its applications to the design and analysis of oncology clinical studies. This field of oncology, now in the midst of evolution owing to rapid advances in biotechnologies and cancer genomics, is becoming one of the most promising disease fields in the shift toward personalized medicine. Modern developments of diagnosis and therapeutics of cancer have also been continuously fueled by recent progress in establishing the infrastructure for conducting more complex, large-scale clinical trials and observational studies. The field of cancer clinical studies therefore will continue to provide many new statistical challenges that warrant further progress in the methodology and practice of biostatistics. This book provides a systematic coverage of various stages of cancer clinical studies. Topics from modern cancer clinical trials include phase I clinical trials for combination therapies, exploratory phase II trials with multiple endpoints/treatments, and confirmative biomarker-based phase III trials with interim monitoring and adaptation. It also covers important areas of cancer screening, prognostic analysis, and the analysis of large-scale molecular data in the era of big data.



Shigeyuki Matsui, Professor, Department of Biostatistics, Nagoya University Graduate School of Medicine, smatsui@med.nagoya-u.ac.jp, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan
John Crowley, President and CEO, Cancer Research and Biostatistics, johnc@crab.org, 1730 Minor Ave STE 1900  Seattle, WA 98101-1468


Autorentext
Shigeyuki Matsui, Professor, Department of Biostatistics, Nagoya University Graduate School of Medicine, smatsui@med.nagoya-u.ac.jp, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan
John Crowley, President and CEO, Cancer Research and Biostatistics, johnc@crab.org, 1730 Minor Ave STE 1900  Seattle, WA 98101-1468


Inhalt
1. Phase I clinical trials.- 2. Phase II clinical trials.- 3. Phase III clinical trials.- 4. Evaluation of surrogate endpoints.- 5. Disease Screening/development of diagnosis.- 6. Analysis of omics data (genomic signature developments etc).- 7. Causal inference in clinical trials and observational studies.

Produktinformationen

Titel: Frontiers of Biostatistical Methods and Applications in Clinical Oncology
Editor:
EAN: 9789811001260
ISBN: 978-981-10-0126-0
Digitaler Kopierschutz: Wasserzeichen
Format: E-Book (pdf)
Herausgeber: Springer
Genre: Medizin
Anzahl Seiten: 438
Veröffentlichung: 03.10.2017
Jahr: 2017
Untertitel: Englisch
Dateigrösse: 9.9 MB