Since the original edition was first published more than a
quarter of a century ago, The Handbook of Autism and Pervasive
Developmental Disorders, Volume 1: Diagnosis, Development,
and Brain Mechanisms, has been the most influential reference
work in the field of autism and related conditions. The new,
updated Fourth Edition takes into account the changes in the
disorders' definitions in the DSM-V and ICD-10 that may have
profound implications for diagnosis and, by extension, access to
services. Along with providing practical clinical advice--including
the role of psychopharmacology in treatment--the handbook
codifies the ever-expanding current body of research throughout
both volumes , offering a wealth of information on the epidemiology
of autism and the genetic, environmental, biochemical, social, and
neuropathological aspects of the disorder. Volume 1 includes:
Information on outcomes in adults with autism spectrum
disorders

A range of issues and interventions important from infancy,
though adolescence and beyond for individuals with autism spectrum
disorders
Current information about play development, including skills,
object play, and interventions
Coverage of the state of genetic, biochemical, and
neuropathological autism research
Chapters on psychopharmacology and medical care in autism and
related conditions

The new edition includes the relevant updates to help readers
stay abreast of the state of this rapidly evolving field and gives
them a guide to separate the wheat from the chaff as information
about autism proliferates.

Autorentext

Fred R. Volkmar, M.D., is Irving B Harris Professor of Child Psychiatry, Pediatrics, and Psychology at the Yale Child Study Center where he directs the autism research program.?He is an associate editor of the Journal of Autism and the American Journal of Psychiatry.?He is the author of several hundred scientific papers and chapters as well as a number of books including?A Practical Guide to Autism: What Every Parent, Teacher and Family Members Needs to Know. Rhea Paul, Ph.D., CCC-SLP SLP, is Professor and Director of the Communication Disorders section in the Developmental Disabilities Clinic at the Yale Child Study Center. She holds a joint appointment at SCSU, where she is Professor of Communication Disorders. Sally J. Rogers, Ph.D., UC Davis M.I.N.D. Institute. Her clinical interests include early intervention for children with autism and social skills groups for autistic adults.?She serves on the editorial board of many publications, including the Journal of Autism and Developmental Disorders. Kevin A.? Pelphrey, Ph.D., is the Harris Associate Professor of Child Psychiatry and director of the Child Neuroscience Laboratory at the Yale Child Study Center.

Zusammenfassung
The newest edition of the most comprehensive handbook on autism and related disorders Since the original edition was first published more than a quarter of a century ago, The Handbook of Autism and Pervasive Developmental Disorders, Volume 1: Diagnosis, Development, and Brain Mechanisms, has been the most influential reference work in the field of autism and related conditions. The new, updated Fourth Edition takes into account the changes in the disorders' definitions in the DSM-V and ICD-10 that may have profound implications for diagnosis and, by extension, access to services. Along with providing practical clinical advice--including the role of psychopharmacology in treatmentthe handbook codifies the ever-expanding current body of research throughout both volumes , offering a wealth of information on the epidemiology of autism and the genetic, environmental, biochemical, social, and neuropathological aspects of the disorder. Volume 1 includes: Information on outcomes in adults with autism spectrum disorders

A range of issues and interventions important from infancy, though adolescence and beyond for individuals with autism spectrum disorders
Current information about play development, including skills, object play, and interventions
Coverage of the state of genetic, biochemical, and neuropathological autism research
Chapters on psychopharmacology and medical care in autism and related conditions
The new edition includes the relevant updates to help readers stay abreast of the state of this rapidly evolving field and gives them a guide to separate the wheat from the chaff as information about autism proliferates.

Inhalt

Contributors xi

Preface xix

VOLUME 1: DIAGNOSIS, DEVELOPMENT, AND BRAIN MECHANISMS

I DIAGNOSIS, EPIDEMIOLOGY, COURSE 1

1 AUTISM AND THE AUTISM SPECTRUM: DIAGNOSTIC CONCEPTS 3
Fred R. Volkmar, Brian Reichow, Alexander Westphal, and David S. Mandell

2 THE BROADER AUTISM PHENOTYPE 28
Brooke Ingersoll and Allison Wainer

3 EPIDEMIOLOGY OF AUTISM SPECTRUM DISORDERS 57
Alison Presmanes Hill, Katharine E. Zuckerman, and Eric Fombonne

4 OUTCOMES IN ADULTS WITH AUTISM SPECTRUM DISORDERS 97
Patricia Howlin

II DEVELOPMENT AND BEHAVIOR 117

5 ASD IN INFANTS AND TODDLERS 121
Katarzyna Chawarska, Suzanne Macari, Fred R. Volkmar, So Hyun Kim, and Frederick Shic

6 SCHOOL-AGE CHILDREN WITH ASD 148
Nirit Bauminger-Zviely

7 ISSUES AND INTERVENTIONS FOR AUTISM SPECTRUM DISORDERS DURING ADOLESCENCE AND BEYOND 176
Lynn Kern Koegel, Robert L. Koegel, Amber R. Miller, and Whitney J. Detar

8 ADULTS WITH AUTISM 191
Carla A. Mazefsky and Susan W. White

9 SOCIAL DEVELOPMENT IN AUTISM 212
Naomi Ornstein Davis and Alice S. Carter

10 LANGUAGE AND COMMUNICATION IN AUTISM 230
So Hyun Kim, Rhea Paul, Helen Tager-Flusberg, and Catherine Lord

11 PLAY DEVELOPMENT IN CHILDREN WITH AUTISM SPECTRUM DISORDERS: SKILLS, OBJECT PLAY, AND INTERVENTIONS 263
Connie Kasari and Ya-Chih Chang

12 IMITATION IN AUTISM SPECTRUM DISORDERS 278
Giacomo Vivanti and Antonia Hamilton

13 NEUROPSYCHOLOGICAL CHARACTERISTICS OF AUTISM SPECTRUM DISORDERS 302
Katherine D. Tsatsanis and Kelly Powell

14 AUTISM AND EMOTION 332
R. Peter Hobson

15 MOTOR CONTROL AND MOTOR LEARNING PROCESSES IN AUTISM SPECTRUM DISORDERS 354
Stefanie Bodison and Stewart Mostofsky

16 SENSORY FEATURES IN AUTISM SPECTRUM DISORDERS 378
Grace T. Baranek, Lauren M. Little, L. Diane Parham, Karla K. Ausderau, and Maura G. Sabatos-DeVito

III NEUROBIOLOGY AND MEDICAL ISSUES 409

17 GENETICS OF AUTISM SPECTRUM DISORDERS 411
Michael Rutter and Anita Thapar

18 ENVIRONMENTAL FACTORS IN THE PRECONCEPTION AND PRENATAL PERIODS IN RELATION TO RISK FOR ASD 424
Kristen Lyall, Rebecca J. Schmidt, and Irva Hertz-Picciotto

19 BIOCHEMICAL BIOMARKERS FOR AUTISM SPECTRUM DISORDER 457
George M. Anderson

20 THE SOCIAL NEUROSCIENCE OF AUTISM SPECTRUM DISORDER 482
James C. McPartland, Rachael M. Tillman, Daniel Y.-J. Yang, Raphael A. Bernier, and Kevin A. Pelphrey

21 THE NEUROPATHOLOGY OF AUTISM 497
Manuel F. Casanova

22 MEDICAL CARE IN AUTISM AND RELATED CONDITIONS 532
Fred R. Volkmar, Justin Rowberry, Oana de Vinck-Baroody, Abha R. Gupta, Jennifer Leung, Judith Meyers, Nita Vaswani, and Lisa A. Wiesner

23 PSYCHOPHARMACOLOGY 556
Lawrence Scahill, Caitlin S. Tillberg, and Andres Martin

Author Index I-1

Subject Index I-39

VOLUME 2: ASSESSMENT, INTERVENTIONS, AND POLICY

IV ASSESSMENT 581

24 SCREENING FOR AUTISM IN YOUNG CHILDREN 585
Lisa V. Ibanez, Wendy L. Stone, and Elaine E. Coonrod

25 DIAGNOSTIC INSTRUMENTS IN AUTISTIC SPECTRUM DISORDERS 609
Catherine Lord, Christina Corsello, and Rebecca Grzadzinski

26 CLINICAL EVALUATION IN MULTIDISCIPLINARY SETTINGS 661
*Fred R…