Willkommen, schön sind Sie da!
Logo Ex Libris

The Plasma Proteins

  • E-Book (pdf)
  • 497 Seiten
(0) Erste Bewertung abgeben
Bewertungen
(0)
(0)
(0)
(0)
(0)
Alle Bewertungen ansehen
The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic cont... Weiterlesen
E-Books ganz einfach mit der kostenlosen Ex Libris-Reader-App lesen. Hier erhalten Sie Ihren Download-Link.
CHF 60.90
Download steht sofort bereit
Informationen zu E-Books
E-Books eignen sich auch für mobile Geräte (sehen Sie dazu die Anleitungen).
E-Books von Ex Libris sind mit Adobe DRM kopiergeschützt: Erfahren Sie mehr.
Weitere Informationen finden Sie hier.
Bestellung & Lieferung in eine Filiale möglich

Beschreibung

The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases.
Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes.
This monograph will be of interest to molecular biologists and biochemists.

Klappentext

The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume I is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases.

Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes.

This monograph will be of interest to molecular biologists and biochemists.



Inhalt

List of Contributors

Preface


Contents of Other Volumes


1 Perspectives-Past, Present, and Future


I. Introduction


II. Historical


III. Characterization of the Plasma Proteins


IV. The Scroll of the Plasma Proteins


V. Genetic Markers in Plasma Proteins


VI. Primary Structure and Three-Dimensional Conformation of Plasma Proteins


VII. Conclusion


References


2 Alpha, Beta, Gamma, Omega-The Roster of the Plasma Proteins


I. Introduction


II. Serum Albumin


III. Thyroxine-Binding Proteins


IV. a- and ß-Glycoproteins in Search of a Function


V. a1-Globulins


VI. a2-Globulins


VII. ß-Globulins


VIII. Minor Low Molecular Weight Proteins with y or Basic Mobility and Unknown Function


IX. Lipoproteins


X. The Complement System


XI. Coagulation Proteins


XII. Immunoglobulins


References


3 Serum Albumin


I. Introduction


II. Purification and Properties


III. Metabolism, Physiological Functions, and Alterations in Disease


IV. Genetic Aspects and Phylogeny


References


4 a1-Acid Glycoprotein


I. Introduction


II. Isolation and Purification


III. Crystallization


IV. Chemical Properties


V. Physicochemical Properties


VI. Immunochemical Properties


VII. Studies on the Structure of the Carbohydrate Moiety


VIII. Polymorphism


IX. The Carbohydrate-Protein Linkage


X. The Amino Acid Sequence


XI. The Amino Acid Substitutions


XII. Homology with Other Plasma Proteins


XIII. Secondary Structure


XIV. Genetically Determined Protein Variants


XV. Metabolism


XVI. Speculations Pertaining to the Biological Role


References


5 Protease Inhibitors in Plasma


I. Introduction


II. a1-Antitrypsin


III. a2-Macroglobulins


IV. Other Protease Inhibitors of Plasma


V. Comparative Biochemistry


References


6 Transferrin


I. Introduction


II. Purification and Physical Properties


III. Chemical Composition and Molecular Structure


IV. Genetic Variation and Population Distribution


V. Physiological Function, Biosynthesis, and Variations in Disease


VI. Phylogenetic Distribution


References


7 Serum Lipoproteins


I. Introduction


II. Intact Lipoproteins


III. Lipoprotein Apoproteins


IV. Human Disorders Associated with Serum Lipoprotein Abnormalities


V. Genetic Polymorphism


VI. Serum Lipoproteins in Species Other than Man


VII. Biosynthesis and Metabolism of Serum Lipoproteins


VIII. Physiological Function and Evolutionary Advantages


IX. Perspectives


References


8 The Complement System


I. Introduction


II. Nomenclature


III. General Molecular Dynamics


IV. The Classical Pathway


V. The Proteins and Reaction Products of the Classical Pathway


VI. The Alternative Pathway


VII. The Proteins and Reaction Products of the Alternative Pathway


VIII. Regulators of the Complement System


IX. Conclusion


References


9 ß2-Microglobulin


I. Introduction


II. Purification and Physical Properties


III. Chemical Composition and Structure


IV. Physiological Function, Biosynthesis, and Catabolism


V. Presence and Function in Cell Membranes


VI. Conclusions


References


Subject Index

Produktinformationen

Titel: The Plasma Proteins
Untertitel: Structure, Function, and Genetic Control
Autor:
EAN: 9780323138086
Digitaler Kopierschutz: Adobe-DRM
Format: E-Book (pdf)
Hersteller: Elsevier Science & Techn.
Genre: Medizin
Anzahl Seiten: 497
Veröffentlichung: 02.12.2012
Dateigrösse: 59.8 MB