The recent explosive growth in the study of status epilepticus (SE), an epileptic seizure that threatens to produce new seizures, has shown that SE is not a single disease, but arises from different substrates of the brain and comprises multifaceted illnesses. In Status Epilepticus: A Clinical Perspective, a panel of senior clinicians critically reviews the many forms of SE, their causes, manifestations, methods of diagnosis, and appropriate treatments. The authors emphasize the disease as encountered by the clinician in the field and the importance of correct recognition and diagnosis. They provide for each form of SE the underlying genetic, biological, and developmental background, the pathophysiological processes, as well as the precipitating factors that lead to an episode. For the difficult problem of diagnosing nonconvulsive SE, they offer detailed syndrome classifications, differential diagnoses, descriptions of seizure "imitators," notes on unusual behavioral and cognitive manifestations, and carefully delineated clinical presentations. Additional highlights include striking EEG reproductions that provide classic examples of patients in SE, SE in very young children and neonates, and an analysis of the cellular physiology and processes occurring during SE.
Comprehensive and up-to-date, Status Epilepticus: A Clinical Perspective offers the neurologic clinician an authoritative review of the diagnosis and treatment of the many forms of this most serious and challenging acute nervous system disorder.

Zusammenfassung
A panel of senior clinicians critically reviews the many forms of status epilepticus (SE), their causes, manifestations, methods of diagnosis, and appropriate treatments. The emphasis is on the disease as encountered by the clinician in the field and the importance of correct recognition and diagnosis. The authors provide for each form of SE the underlying genetic, biological, and developmental background, the pathophysiological processes, as well as the precipitating factors that lead to an episode. For the difficult problem of diagnosing nonconvulsive SE, they offer detailed syndrome classifications, differential diagnoses, descriptions of seizure "imitators," notes on unusual behavioral and cognitive manifestations, and carefully delineated clinical presentations. Additional highlights include striking EEG reproductions that provide classic examples of patients in SE, SE in very young children and neonates, and an analysis of the cellular physiology and processes occurring during SE.

Inhalt
General Topics.- History of Status Epilepticus.- Types of Status Epilepticus.- Differential Diagnosis of Status Epilepticus.- Epidemiology of Status Epilepticus.- The Electroencephalogram in Status Epilepticus.- Generalized Convulsive and Focal Status Epilepticus.- Generalized Convulsive Status Epilepticus.- Focal Status Epilepticus.- Basic Considerations.- Cellular Physiology of Status Epilepticus.- Cellular Damage and the Neuropathology of Status Epilepticus.- Nonconvulsive Status Epilepticus.- Clinical Presentations of Nonconvulsive Status Epilepticus.- Cognitive Manifestations of Status Epilepticus.- Nonconvulsive Status Epilepticus.- Treatment.- Treatment of Generalized Convulsive Status Epilepticus.- Treatment of Refractory Status Epilepticus.- Treatment of Nonconvulsive Status Epilepticus.- Pediatric and Neonatal Status Epilepticus.- Status Epilepticus in Children.- Status Epilepticus in Neonates.