Experts in the fields of neurology, neuroscience, neurobiology and psychiatry review and present novel findings of basic and clinical research on extrapyramidal disorders and allied conditions. New insights on the nature of extrapyramidal dysfunction and its therapy in the fields of neurology, psychiatry and neuroscience are presented.

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I. Heider et al.: Dopaminergic neurotoxicity of homocysteine and its derivatives in primary mesencephalic cultures.- D. Woitalla et al.: MTHFR C 677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease.- A. S. Glass et al.: Screening for mutations in synaptotagmin XI in Parkinson's disease.- A. Heinz et al.: Depletion and restoration of endogenous monoamines affects ß-CIT binding to serotonin but not dopamine transporters in non-human primates.- J. Uekermann et al.: Differential executive control impairments in early Parkinson's disease.- S. Muhlack et al.: Simple movement sequences better correlate to levodopa plasma levels than complex ones.- Ch. Börnke et al.: Clinical effects of repetitive transcranial magnetic stimulation versus acute levodopa challenge in Parkinson's disease.- G. Schmid et al.: Impact of apomorphine on BOLD signal during movement in normals.- Th. Müller et al.: Worsened motor test performance following acute apomorphine injection in previously untreated patients with Parkinson's disease.- D. Woitalla et al.: Transdermal lisuride delivery in the treatment of Parkinson's disease.- C. Saft, C. et al.: Congruent deterioration of complex and simple movements in patients with Huntington's disease.- N. Brune et al.: Methyltetrahydrofolate reductase polymorphism influences onset of Huntington's disease.- J. Andrich et al.: Coenzyme Q10 serum levels in Huntington's Disease.- A. Beister et al.: The N-methyl-D-aspartate antagonist memantine retards progression of Huntington's disease.- Th. Postert et al.: Transcranial sonography in spinocerebellar ataxia type 3.- L. Schöls et al.: Therapeutic strategies in Friedreich's ataxia.- V. G. Hösing et al.: Cholecystokinin- and cholecystokinin-B-receptor gene polymorphgisms in panic disorder