This textbook describes the biology of different stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal cord blood, neural and muscle stem cells and also covers induced pluripotent stem cells and their applications. Further, it includes chapters on organoids, stem-cell based disease modelling, extracellular vesicles and one chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on lectures of the international master program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and participation of collaborating professors from Tongji University Shanghai, the book is a valuable source for students, postdocs and researchers, who would like to have introductory chapters on stem cell biology. It also offers essential insights for physicians and dentists wishing to expand their knowledge.

This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Autorentext

Beate Brand-Saberi is a Professor of Anatomy and Cell Biology and Head of the Department of Anatomy and Molecular Embryology at the Ruhr-University in Bochum, Germany.

She has been a Visiting Professor at the Department of Life Sciences at the University of Lanzhou, China and at the Shanghai Jiao Tong University, China.

Prof. Brand-Saberi initiated the international, interdisciplinary masters program on stem cell research at the Ruhr University, Bochum on which this textbook is based.

Klappentext

This textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material.

Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge.

This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Inhalt

1. Hematopoietic stem cells2. Mesenchymal stem cells

2. Cord blood stem cells

3. Induced pluripotent stem cells

4. Epigenetic regulation in somatic cell reprogramming

5. MET in reprogramming

6. Extracellular vesicles

7. Neural stem cells

8. Neural stem cell niche

9. Human pluripotent stem cells and neural regeneration

10. Organoids

11. Ethical aspects of human stem cell research