Equine Clinical Immunology

Equine Clinical Immunology offers comprehensive information on equine immunological disorders. Provides a complete, equine-specific reference on clinical immunology Focuses on clinically relevant information for the diagnosis and treatment of horses with immune disorders Illustrates the concepts discussed using drawings, photographs, and tables Presents key concepts, clinical assessment information, and treatment approaches in text boxes for ease of use Offers a practical, clinically oriented approach ideal for equine specialists

Autorentext

M. Julia B. Felippe, MedVet, MSc, PhD, DACVIM, is an Associate Professor of Large Animal Medicine and Veterinary Curriculum Director at Cornell University's College of Veterinary Medicine in Ithaca, New York, USA.

Klappentext

Equine Clinical Immunology offers comprehensive information on equine immunological disorders. Focusing specifically on diagnosing, treating, and managing conditions of the immune system in horses, the book is edited by a leading clinician in this area and contributed to by top experts in equine immunology. Offering a practical, clinically oriented approach, Equine Clinical Immunology covers topics ranging from basic immunology and pathophysiology to specific immune disorders, testing, vaccination, and stem cell therapy.

Designed to present a complete resource on the topic, the book uses illustrations, photographs, and tables to explain the concepts discussed. Text boxes provide key concepts, clinical assessment, and treatment approaches. Equine Clinical Immunology offers a valuable resource for equine specialists seeking information related to immune disorders in equine patients.

**Key features

• Provides a complete, equine-specific reference on clinical immunology
• Focuses on clinically relevant information for the diagnosis and treatment of horses with immune disorders
• Illustrates the concepts discussed using drawings, photographs, and tables
• Presents key concepts, clinical assessment information, and treatment approaches in text boxes for ease of use
• Offers a practical, clinically oriented approach ideal for equine specialists

Zusammenfassung
Equine Clinical Immunology offers comprehensive information on equine immunological disorders.

• Provides a complete, equine-specific reference on clinical immunology
• Focuses on clinically relevant information for the diagnosis and treatment of horses with immune disorders
• Illustrates the concepts discussed using drawings, photographs, and tables
• Presents key concepts, clinical assessment information, and treatment approaches in text boxes for ease of use
• Offers a practical, clinically oriented approach ideal for equine specialists

Inhalt

Contributors, ix

Preface, xi

1 The Immune System, 1
M. Julia B. Felippe

1.1 Definition, 1

1.2 The organs of the immune system, 1

1.3 The immune cells and soluble molecules, 2

1.4 B and T cell activation in lymphoid tissues, 6

1.5 When the immune response goes wrong, 9

References, 10

2 The Immune System of the Young Horse, 11
Rebecca L. Tallmadge

2.1 Definition, 11

2.2 Equine immune system development, 11

2.3 Unique susceptibilities and disorders of young horses, 16

2.4 Vaccinology teaches about neonatal immunity, 18

References, 18

3 The Immune System of the Older Horse, 23
Amanda A. Adams and David W. Horohov

3.1 Definition, 23

3.2 Clinical conditions associated with aging, 23

3.3 Immunosenescence and vaccination, 23

3.4 Nutrition in enhancing immunity in the old horse, 26

3.5 Conclusion, 27

References, 27

4 Anaphylaxis, 31
Rolfe M. Radcliffe

4.1 Definition, 31

4.2 Signalment and clinical signs, 31

4.3 Immunologic mechanisms and etiologic associations, 32

4.4 Diagnostics, 33

4.5 Treatment, 34

4.6 Prevention, 36

4.7 Prognosis and clinical outcomes, 37

References, 37

5 Allergy, 39
Bettina Wagner

5.1 Definition, 39

5.2 Culicoides hypersensitivity, 39

5.3 Urticaria, 43

5.4 Recurrent airway obstruction, 44

References, 44

6 Immune-Mediated Cytopenias, 47
Thomas J. Divers

6.1 Definition, 47

6.2 Immune-mediated hemolytic anemia, 47

6.3 Immune-mediated thrombocytopenia, 50

6.4 Immune-mediated neutropenia, 53

References, 54

7 Bullous Diseases of the Skin and Mucosa, 55
Jeanine Peters-Kennedy and Rebecca E. Ruby

7.1 Definition, 55

7.2 Immune-mediated bullous dermatoses, 55

7.3 Pemphigus complex, 57

7.4 Cutaneous adverse drug reactions, 61

7.5 Erythema multiforme, 62

7.6 Lupus erythematosus, 64

References, 65

8 Serum Sickness, 69
Lais R.R. Costa

8.1 Definition, 69

8.2 Signalment and clinical signs, 69

8.3 Immunologic mechanisms and etiologic associations, 69

8.4 Diagnostics, 71

8.5 Treatment and prevention, 71

References, 72

9 Vasculitis, 73
James S. W. Prutton and Nicola Pusterla

9.1 Definition, 73

9.2 Signalment and clinical signs, 73

9.3 Immunologic mechanisms and etiologic associations, 73

9.4 Diagnostics, 75

9.5 Treatment, 75

9.6 Thrombophlebitis, 75

9.7 Pastern and cannon leukocytoclastic vasculitis, 76

9.8 Drug-induced vasculitis, 76

9.9 Photo-activated vasculitis (photodynamic drugs), 77

9.10 Strongylus vulgaris, 77

9.11 Equine granulocytic anaplasmosis, 77

9.12 Equine viral arteritis, 78

9.13 Equine herpesvirus-1, 78

9.14 African horse sickness, 78

References, 79

10 Purpura Hemorrhagica, 83
Laszlo M. Hunyadi and Nicola Pusterla

10.1 Definition, 83

10.2 Signalment and clinical signs, 83

10.3 Immunologic mechanisms and etiologic associations, 83

10.4 Diagnostics, 84

10.5 Treatment and prevention, 85

References, 86

11 Glomerulonephritis, 87
M. Julia B. Felippe

11.1 Definition, 87 11.2 Signalment and clinical signs, 87</p&gt...