Energy Metabolism and Obesity: Research and Clinical Applications is a compilation of highly informative reviews written by undisputed leaders in the field. These authors elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them. Understanding the physiology of energy storage and partitioning has become quite a daunting task. This title enables researchers and clinicians to face the challenge of understanding this complex topic and applying the information to the practice of obesity prevention and treatment. The excellent overviews in this book will undoubtedly provide readers with a better understanding of the multifaceted entity of obesity.

Zusammenfassung

This unique and authoritative book presents an up-to-date overview of the many aspects of energy balance and its relationships to disease processes resulting from excess energy consumption and storage. It provides a comprehensive treatment of important research and clinical aspects of energy metabolism and obesity. It will be a valuable resource for endocrinologists, diabetes specialists, internists and family practitioners.

Inhalt
Molecular Physiology of Monogenic and Syndromic Obesities in Humans.- Leptin Signaling In the Brain.- Inactivating Melanocortin 4 Receptor Mutations and Human Obesity.- The Role of Central Melanocortins in Cachexia.- The Efferent Arm of the Energy Balance Regulatory Pathway: Neuroendocrinology and Pathology.- Adiponectin: A Multifunctional Adipokine.- The Role of the Gastrointestinal Hormones Ghrelin, Peptide YY, and Glucagon-like Peptide-1 in the Regulation of Energy Balance.- The Role of Growth Hormone Secretagogues and Ghrelin in Feeding and Body Composition.- Interaction Between Physical Activity and Genetic Factors in Complex Metabolic Disease.- 11?-Hydroxysteroid Dehydrogenase Type 1 and Obesity.- Prader-Willi Syndrome: A Model of Disordered Energy Homeostasis.- Antipsychotic MedicationInduced Weight Gain and Risk for Diabetes and Cardiovascular Disease.- Treatment of Insulin Resistance in Youth: The Role of Metformin.- The Surgical Approach to Morbid Obesity.