Membrane proteins, lipids and their glycosylated derivatives are discussed both with respect to their biosynthesis as well as regarding their mutual interaction and assembly into functional membranes. Topics cover a large variety of systems and cells: investigation on virus membranes as well as pro- and eukaryotic cells are included.

Inhalt

Glycolipids-intracellular movement and storage diseases..- The biology of lipid-containing membrane proteins..- Preferential release of glycosyl-phosphatidylinositol anchored proteins from human red blood cells during vesiculation..- Structures formed by membrane lipids: physicochemical properties and possible biological relevance for membrane function..- Studies of the metabolism and function of sn-1-stearoyl-2-arachidonoyl lipids in animal cells..- Involvement of the intracellular lipid traffic during plasma membrane biogenesis in higher plants..- Evidence for an intermembrane transport of lipids to peripheral nerve myelin in vivo by a novel pulsed wave procedure..- Phospholipid localization and mobility in Plasmodium infected erythrocytes..- Lipid transport in Plasmodium falciparum - infected erythrocyte membranes..- Membrane properties modulate the activity of a yeast phosphatidylinositol/phosphatidylcholine transfer protein..- Protein glycosylation: oligosaccharyl transferase and a novel recognition protein..- Mutants: a fruitful approach to the understanding of asparagine-linked glycosylation in eukaryotic cells..- Functional and structural aspects of gramicidin-lipid interactions..- Influenza virus mediated membrane fusion: the identification of fusion intermediates using modern cryotechniques..- Cell-free systems for studying the pathway of receptor mediated endocytosis..- Plasma membrane biogenesis in polarized rat hepatocytes..- Genetic approaches to the study of protein targeting..- Signals and components involved in the translocation of proteins across the endoplasmic reticulum membrane..- Signal peptide-lipid interactions and their significance for protein translocation in Escherichia coli..- The enzymology of bacterial protein export..- Components and mechanisms involved in colicin release and colicin uptake across the cell envelope in Escherichia coli..- Protein transport into and inside the chloroplast.- Import of preprocecropin A and related precursor proteins into the endoplasmic reticulum..- Soluble and membrane-associated factors required for protein translocation into the yeast endoplasmic reticulum..- Dynamic interactions between membrane constituents studied by biophysical techniques and functional reconstitution of membrane proteins into lipid bilayers..