This volume collects contributions on leading figures in mechanism and machine science (MMS) from Spain and Ibero-America over the last two centuries. The contributions examine scientists whose work resulted in relevant technical-scientific achievements, with an impact on technology and science in the historical evolution of MMS fields, and with an influence on the development of society at large. Biographical notes describing the efforts and achievements of these persons are included as well, but a technical survey is the core of each chapter, offering a modern interpretation of their legacy.