Current and Emerging Technologies for the Diagnosis of Microbial Infections

Current and Emerging Technologies in Microbial Diagnostics, the latest volume in the Methods in Microbiology series, provides comprehensive, cutting-edge reviews of current and emerging technologies in the field of clinical microbiology.

The book features a wide variety of state-of-the art methods and techniques for the diagnosis and management of microbial infections, with chapters authored by internationally renowned experts. This volume focuses on current techniques, such as MALDI-TOF mass spectroscopy and molecular diagnostics, along with newly emerging technologies such as host-based diagnostics and next generation sequencing.

• Written by recognized leaders and experts in the field
• Provides a comprehensive and cutting-edge review of current and emerging technologies in the field of clinical microbiology, including discussions of current techniques such as MALDI-TOF mass spectroscopy and molecular diagnostics
• Includes a broad range and breadth of techniques covered
• Presents discussions on newly emerging technologies such as host-based diagnostics and next generation sequencing

Inhalt

1. **Total Laboratory Automation in Clinical Bacteriology
   **Susan M. Novak-Weekley and Elizabeth M. Marlowe
2. **MALDI-TOF Mass Spectrometry for Microorganism Identification
   **Lori Bourassa and Susan M. Butler-Wu
3. **POC Tests in Microbial Diagnostics: Current Status
   **Luc Bissonnette and Michel G. Bergeron
4. **Molecular Diagnostics in the Diagnosis of Parasitic Infection
   **Bobbi S. Pritt
5. **Clinical Applications of Quantitative Real-Time PCR in Virology
   **Julia Engstrom-Melnyk, Pedro L. Rodriguez, Olivier Peraud and Raymond C. Hein
6. **Low Density TaqMan® Array Cards for the Detection of Pathogens
   **Jude Heaney, Kathryn Rolfe, Nicholas S. Gleadall, Jane S. Greatorex and Martin D. Curran
7. **Invasive Fungal Infections and Approaches to Their Diagnosis
   **Michael A. Pfaller
8. **Technical and Software Advances in Bacterial Pathogen Typing
   **Linda Chui and Vincent Li
9. **Molecular Strain Typing and Characterisation of Toxigenic *Clostridium difficile
   Tanis C. Dingle and Duncan R. MacCannell*
10. Accurate Whole Genome Sequencing-Based Epidemiological Surveillance of ***Mycobacterium tuberculosis
    *Hannes Pouseele and Philip Supply
11. **Solid and Suspension Microarrays for Microbial Diagnostics
    **Steve Miller, Ulas Karaoz, Eoin Brodie and Sherry Dunbar
12. **Gene Amplification and Sequencing for Bacterial Identification
    **Susanna K. P. Lau, Jade L. L. Teng, Chi-Chun Ho and Patrick C. Y. Woo
13. **Host-Based Diagnostics for Detection and Prognosis of Infectious Diseases
    **William E. Yang, Christopher W. Woods and Ephraim L. Tsalik
14. **MALDI-TOF Mass Spectrometry in the Clinical Microbiology Laboratory; Beyond Identification
    **Sören Schubert and Markus Kostrzewa
15. **Next-Generation Sequencing for Pathogen Detection and Identification
    **Kenneth G. Frey and Kimberly A. Bishop-Lilly
16. **Virology - The Next Generation from Digital PCR to Single Virion Genomics
    **Richard Allen White III, Jessica N. Brazelton de Cárdenas and Randall T. Hayden
17. **Artificial Nucleic Acid Probes and Their Applications in Clinical Microbiology
    ***Alon Singer and Yi-Wei Tang
    *