The LNCS 15915 constitutes the proceedings from the 38th International Conference on Computer Animation and Social Agents, CASA 2025, held in Strasbourg, France, during June 2-4, 2025.

The 20 papers (17 from the main conference and 3 from the AniNex workshop) presented were carefully reviewed and selected from 82 submissions. These papers focus on various aspects of Computer Animation and Social Agents, such as Motion Capture & Retargeting, Physics-based Animation, Vision-based Techniques, Behavioral Animation, Facial Animation, Image-based Animation, Virtual Humans, Crowd Simulation, AI-based Animation, Deep Learning Methods, Virtual Humans and Avatars, and 3D Physiological Humans.