These two volumes constitute the selected and revised papers presented at the Second International Conference on Communication, Networks and Computing, CNC 2022, held in Gwalior, India, in December 2022. The 53 full papers were thoroughly reviewed and selected from the 152 submissions. They are organized in topical sections on Wired and Wireless Communication Systems, Networks and Information Security, Electronics Circuits for Communication Systems, High Dimensional Data Representation & Processing, Computing Techniques for Efficient Networks Design and Vehicular Technology and Applications