Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida Opioids in Preclinical and Clinical Trials; by H. Nagase and H. Fujii Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M. Spetea 14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actions; by J. W. Lewis and S. M. Husbands Nonpeptidic Delta (d) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?; by S. N. Calderon Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects; by K. M. Lovell, K. M. Prevatt-Smith, A. Lozama and T. E. Prisinzano Synthesis of Novel Basic Skeletons Derived from Naltrexone; by H. Nagase and H. Fujii Twin and Triplet Drugs in Opioid Research; by H. Fujii 3D-Pharmacophore Identification for -Opioid Agonists Using Ligand-Based Drug-Design Techniques; by N. Yamaotsu and S. Hirono