This volume is focused on subjects related to cerebral veins under normal conditions and after brain injuries especially acute stroke. Some chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and some chapters are invited, but all written by members of world leading laboratories of stroke and central nervous system studies. The contents cover both clinical and bench studies, from basic components of cerebral neurovascular network and venous stroke animal models to clinical venous disorders, from venous imaging, venous regulation, and venous collateral circulation to acute and chronic brain injuries including pediatric and neurosurgical disorders to hemorrhagic stroke. Min Lou, Professor and Vice Chair of Neurology at the Second Affiliated Hospital of Zhejiang University. Jianmin Zhang, Professor and Chair of Neurosurgery at the Second Affiliated Hospital of Zhejiang University. Yilong Wang, Professor of Neurology, Beijing Tiantan Hospital. Yan Qu, Professor and Director of Neurosurgery at the Second Affiliated Hospital of Air Force Medical University, Xi'an, China. Wuwei (Wayne) Feng, Professor of Neurology Medical University of South Carolina, USA. Xunming Ji, Professor of Neurosurgery, Beijing Xuanwu Hospital. John H. Zhang, Professor of Anesthesiology and Physiology at Loma Linda University School of Medicine, Loma Linda, CA, USA.

Zusammenfassung
Provides important information from anatomy to pathophysiology and covers most neurological disorders that involve venous circulation. Venous circulation has not been extensively studied and we know relatively little about cerebral venous circulation. Venous circulation contributes to half of the brain circulation and about 70% of the blood in the brain is venous blood. Veins and venules play extremely important roles in brain circulation especially during pathologies such as brain edema, BBB disruption, elevation of intracranial pressure during and after ischemic and hemorrhagic stroke events, traumatic brain injury, neurodegerative disorders, in adults and newborns. Occlusion of veins or sinuses by thrombus, compression of veins and venules by tumor and edematous tissues, elevation of venous pressure during cranial hypertension, all lead to fatal insults such as venous infarction and hemorrhage.

Inhalt

1. History of Cerebral Venous System - John Zhang, Anesthesiology, Loma Linda University, USA

   2. Anatomy and Physiology of Cerebral Venous System, imaging MRV - Fengjiao Man, Weijian Jiang, PLA Rocket Force General Hospital, Beijing, China

   3. Pharmacology of cerebral veins - Zhenni Guo/Yi Yang, Neurology, Jilin University, Jilin, China

   4. Genetic impact of Cerebral Vein - Yujie Chen, Hua Feng, Neurosurgery, The Third Military Medical University, Chongqing, China

   5. Cerebral venous collateral circulation- Lusha Tong/Min Lou, Neurology, Zhejiang University, Hangzhou, China

   6. The Pathophysiology of Cerebral Vein - Qinwu Yang, Neurology, The Third Military Medical University, Chongqing, China
      6.1. Venous sinus
      6.2. Cortical veins
      6.3. Deep veins

   7. Vein-Mediated Pathophysiological Change in brain injury
      7.1. Involvement of Cerebral Venous System in Ischemic Stroke - Lusha Tong/Min Lou, Neurology, Zhejiang University, Hangzhou, China

   7.2. Role of Cerebral Venous System in Hemorrhagic Stroke - Yan Qu, Neurosurgery, The Fourth Military Medical University, Xian, China

   7.3. Role of Cerebral Venous System in Traumatic Brain Injury - Yan Qu, Neurosurgery, The Fourth Military Medical University, Xian, China

   7.4. Role of Cerebral Venous System in Pediatric Brain Injury - Qinwu Yang, Neurology, The Third Military Medical University, Chongqing, China

   7.5. Role of Cerebral Venous System in Neurodegenerative Disorders - Yan Qu, Neurosurgery, The Fourth Military Medical University, Xian, China

   7.6. Cerebral Venous Thrombosis - Qinwu Yang, Neurology, The Third Military Medical University, Chongqing, China

7.7. Pediatric venous thrombosis - Wuwei Feng, Neurology, South Carolina, USA

8. Imaging of Cerebral Vein in Acute Brain Injury - Min Lou, Neurology, Zhejiang University, Hangzhou, China

9. Diagnosis Methods of Cerebral Vein in Brain Injury - Yujie Chen/Hua Feng, Neurosurgery, The Third Military Medical University, Chongqing, China

10. Pharmacotherapy targeting Cerebral Venous System - Yilong Wang, Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

11. Implications for Treatment of Cerebral Venous System - Zhanhui Feng/ John Zhang, Neurology, Guizhou University, China/Anesthesiology, Loma Linda University, USA

12. Endovascular Therapy for venous Disorders - Jianmin Zhang, Neurosurgery, Zhejiang University, Hangzhou, China

13. Toward Precision medicine in acute brain injury: The Role of Cerebral Venous System - Jianmin Zhang, Neurosurgery, Zhejiang University, Hangzhou, China

14. Case studies Jianmin Zhang, Neurosurgery, Zhejiang University, Hangzhou, China

15. Animal models of venous stroke - Qin Hu, Shanghai Jiaotong University, Shanghai, China

16. Venous role in stroke recovery - Wuwei Feng, Neurology, South Carolina, USA

17. Venous systems and brain edema - Mengzhou Xue, Neurology, Zhenzhou University, Zhenzhou, China

18. Venous role and evaluation and complications in neurosurgery - Qinhai Huang, Neurosurgery, The Second Military Medical University, Shanghai, China

19. The role of veins in arterial and venous malformation, AV fistula, Dura fistula, pathophysiology and treatment - Qinhai Huang, Neurosurgery, The Second Military Medical University, Shanghai, China

20. Pseudo tumor cerebri (idiopathic intracranial hypertension) - Wuwei Feng, Neurology, South Carolina, USA