Proceedings of the NATO Advanced Research Workshop on Cellular and Molecular Biology of Myelination, held at Monastery Ohrbeck near Osnabrück, FRG, August 28-September 2 1989

Inhalt

Steps in Glial Cell Differentiation and Myelinogenesis.- The O-2A Progenitor During Development and Remyelination.- Regulation of Oligodendrocyte Progenitor Development: Antibody-Perturbation Studies.- Oligodendrocyte Differentiation: Developmental and Functional Subpopulations.- Long-Term Tissue Cultures of Newborn Rat Optic Nerve Cells: Functional Differentiation of Glia and Appearance of Neuron-Like Cells.- Distribution of Myelin Protein Gene Products in Actively-Myelinating Oligodendrocytes.- Immuno-Localization of Sodium Channels in Axon Membrane and Astrocytes and Schwann Cells in Vivo and in Vitro.- Demyelination, Remyelination and Glial Cell Transplantation.- Some Aspects of Mechanisms of Inflammatory Demyelination.- Tellurium-Induced Demyelination.- Oligodendrocyte Reaction to Axonal Damage.- Glial Cell Differentiation in Regeneration and Myelination.- Aggregating Brain Cell Cultures: A Model to Study Myelination and Demyelination.- The Transplantation of Glial Cells into Areas of Primary Demyelination.- Remyelination of a Chemically Induced Demyelinated Lesion in the Spinal Cord of the Adult Shiverer Mouse by Transplanted Oligodendrocytes.- Signal Transduction and Regulatory Events in Myelin-Forming Cells.- cAMP-Dependent Protein Kinase: Subunit Diversity and Functional Role in Gene Expression.- Protein Kinase C in neuronal Cell Growth and Differentiation.- Oligodendrocyte-Substratum Interaction Signals Cell Polarization and Secretion.- Proteinkinase A and C are Involved in Oligodendroglial Process Formation.- Growth Factors in Human Glial Cells in Culture.- Regulation of Oligodendrocyte Development by Insulin-Like Growth Factors and Cyclic AMP.- Platelet-Derived Growth Factor and Its Receptors in Central Nervous System Gliogenesis.- Transfected Cells as a Tool in Myelin Research.- Gene Transfer of Rat Mature Oligodendrocytes and O-2A Progenitor Cells with the ß-Galactosidase Gene.- Immortalization of Oligodendrocyte Precursors from the Optic Nerve of the Rat with a Temperature-Sensitive form of the SV40T Antigen Using a Retrovirus Vector.- Expression of Nervous System cDNAs in Glial and Non-Glial Cell Lines.- Phylogenetic Aspects of Myelination.- Myelin and Myelin-Forming Cells in the Brain of Fish - A Cell Culture Approach.- Myelin Proteolipid Protein: Cladistic Tool to Study Vertebrate Phylogeny.- Phylogentic Asrects of Myelin Structure.- Components and Structures of Myelin.- Composition and Metabolism of Myelin Cerebrosides and Gangliosides.- Receptor Activity and Signal Transduction in Myelin.- Myelin Oligodendrocyte Glycoprotein - A Model Target Antigen for Antibody Mediated Demyelination.- Role of an Endogenous Mannosyl-Lectin in Myelination and Stabilization of Myelin Structure.- Myelin Gene Regulation in the Peripheral Nervous System.- GTP-Binding Proteins Associated with CNS Myelin.- Molecular Biology of Genes Coding for Myelin Proteins.- Molecular Approaches to the Study of the Regulation of Myelin Synthesis.- From Myelin Basic Protein to Myelin Deficient Mice.- Proteolipid Protein: From the Primary Structure to the Gene.- Developmental Expression of the Myelin Proteolipid Protein Gene.- The Myelination Cascade.