Addressing the regulation of the eukaryotic cell cycle, this book brings together experts to cover all aspects of the field, clearly and unambiguously, delineating what is commonly accepted in the field from the problems that remain unsolved. It will thus appeal to a large audience: basic and clinical scientists involved in the study of cell growth, differentiation, senescence, apoptosis, and cancer, as well as graduates and postgraduates.

Inhalt

Regulation of G1 Phase.- Regulation of S Phase.- Regulation of the G2 to M Transition.- Regulation of CDKs by Phosphorylation.- Regulation of the Cell Cycle by CDK Inhibitors.- Regulation of the Cell Cycle by the Ubiquitin Pathway.- Regulation of the Cell Cycle by the Rb Tumor Suppressor Family.- Control of Cell Proliferation by Myc Proteins.- Growth Regulation by the E2F and DP Transcription Factor Families.