This book provides a comprehensive framework for treatment and management of bronchopulmonary dysplasia. In recent years great strides have been made toward understanding the pathogenesis and clinical aspects of BPD, which is the most common chronic lung disease affecting infants. This one-stop resource is written by leading scientists and clinicians in the field, and chapters discuss the most recent developments in the basic scientific, translational, and clinical characteristics of the disease. Topics such as hyperoxia, pre- and post-natal inflammation, and genetics and biomarkers of BPD are included, as well as non-invasive ventilation techniques, nutrition, and radiology applications from pre-term birth to adulthood. The book closes with an in-depth look at emerging therapeutic options for prevention of BPD.Bronchopulmonary Dysplasiais an essential volume for all neonatologists, pediatric pulmonologists, and scientists interested in developmental disorders of the lung.

Autorentext

Vineet Bhandari, MBBS, MD, DM

Chief, Section of Neonatal-Perinatal Medicine

Professor of Pediatrics, Obstetrics and Gynecology

Drexel University College of Medicine

St. Christopher's Hospital for Children / Hahnemann University Hospital / Temple University Hospital

Department of Neonatology (Pediatrics)

Philadelphia, PA, USA

Inhalt

Hyperoxia in the pathogenesis of Bronchopulmonary Dysplasia.- Invasive mechanical ventilation in the pathogenesis of Bronchopulmonary Dysplasia.- Pre- and post-natal inflammation in the pathogenesis of Bronchopulmonary Dysplasia.- Mycoplasma in Bronchopulmonary Dysplasia.- Chronic obstructive pulmonary disease following Bronchopulmonary Dysplasia.- Genetics of Bronchopulmonary Dysplasia.- Biomarkers of Bronchopulmonary Dysplasia.- Pathology of Bronchopulmonary Dysplasia.- Bronchopulmonary Dysplasia: Definitions and Epidemiology.- Oxygen modulation and Bronchopulmonary Dysplasia: Delivery Room and Beyond.- Non-invasive ventilation for the prevention of Bronchopulmonary Dysplasia.- Nutrition in Bronchopulmonary Dysplasia: In the NICU and Beyond.- Radiology of Bronchopulmonary Dysplasia: from preterm birth to adulthood.- Pulmonary Hypertension in Bronchopulmonary Dysplasia.- Pulmonary Function in Survivors of Bronchopulmonary Dysplasia.- Stem cells for the prevention of Bronchopulmonary Dysplasia.- Less invasive surfactant administration (LISA) for the prevention of Bronchopulmonary Dysplasia.- Anti-Inflammatory Agents for the Prevention of Bronchopulmonary Dysplasia.