New research findings based on ambulatory and self-monitoring of blood pressure and heart rate have signaled the maturation of cardiovascular chronobiology and led to marked improvements in the physician's ability to detect various clinical entities in those patients suffering from hypertension and vascular diseases. In Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, William B. White, MD, and a panel of highly experienced clinicians critically review every aspect of out-of-office evaluation of blood pressure, including home and ambulatory pressure, the relationship between whole-day blood pressure and the cardiovascular disease process, and the effects of numerous antihypertensive therapies on these blood pressure parameters. The world-class opinion leaders writing here describe all the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders and demonstrate that ambulatory blood pressure values are independent predictors of cardiovascular morbidity and mortality. They also discuss the methodology of out-of-office blood pressure monitoring, its potential in clinical trials and the general management of patients, and its usefulness during antihypertensive drug development.
Comprehensive and leading-edge, Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics provides a ground-breaking demonstration of the importance of home and ambulatory blood pressure monitoring that is already being rapidly translated into better care for millions of hypertensives today.

Klappentext

Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics provides information that will be especially useful to all who care for hyperten­ sive patients. The various chapters provide a full account of the mounting sci­ entific evidence that blood pressure recordings need to be obtained for proper diagnosis, prognosis, and therapy for these patients. The contributors are each directly involved in clinical studies ofhome and ambulatory blood pressure moni­ toring, as well as of the relationship of circadian variations in heart rate and blood pressure to cardiovascular events. As a longtime observer of the multiple facets of clinical hypertension, I have been greatly impressed with the rapid advances in this area over the last two decades. Out-of-office blood pressure monitoring has grown from a curi­ osity to a necessity. In order to improve the currently inadequate control of hypertension throughout the world, such monitoring should become routine in the diagnosis and treatment of every patient. The evidence for the role of out-of-office monitoring that is so well described in Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics should serve as a stimulus for the more widespread adoption of the procedure. Once this is understood, the constraints on the broader clinical use of ambulatory monitoring that now exist in the United States will be lifted as the value of such information becomes more generally recognized. In the meantime, self-recorded home measurements should be more widely utilized.

Inhalt

Section I. Techniques in Out-of-Office Blood Pressure Monitoring. Self-Monitoring of Blood Pressure, Thomas G. Pickering, and D.Phil. Evaluation of Journals, Diaries, and Indexes of Worksite and Environmental Stress, Gary D. James. Electronic Activity Recording in Cardiovascular Disease, George A. Mansoor . Ambulatory Monitoring of the Blood Pressure, Yusra Anis Anwar and William B. White. Section II. Concepts in the Circadian Variation of Cardiovascular Disease. Circadian Rhythm and Environmental Determinants of Blood Pressure Regulation in Normal and Hypertensive Conditions, Francesco Portaluppi and Michael H. Smolensky.Circadian Variation of the Blood Pressure in the Population at Large,Hilde Celis and Jan A. Staessen. The Importance of Heart Rate in Determining Cardiovascular Risk, Paolo Palatini . Impact of Sodium, Potassium, the Sympathetic Nervous System, and the Renin-Angiotensin System on the Circadian Variability in Blood Pressure, Domenic A. Sica and Dawn K. Wilson. Prognostic Value of Ambulatory Blood Pressure Monitoring, Paolo Verdecchia and Giuseppe Schillaci , Ospedale R. Silvestrini. Circadian Rhythm of Myocardial Infarction and Sudden Cardiac Death, Craig A. Chasen and James E. Muller. Seasonal, Weekly and Circadian Variability of Ischemic and Hemorrhagic Stroke, Tudor D. Vagaonescu, Robert A. Phillips, Stanley Tuhrim. Hypertension Section and Cardiac Health Program, Zena and Michael A. Wiener. Section III. Twenty-four hour blood pressure monitoring and therapy. Cardiovascular Chronobiology and Chronopharmacology: Importance of Timing of Dosing , Bjørn Lemmer,. Advances in Ambulatory Blood Pressure Monitoring for the Assessment of Antihypertensive Therapy in Research and Practice,William B. White.