The increasing incidence of bladder cancer in the United States and worldwide offers an excellent opportunity to better understand the biology of this cancer and to apply clinically relevant research in the treatment room. In Bladder Cancer: Current Diagnosis and Treatment, Michael J. Droller and a panel of experienced clinicians and researchers bring their strong background in clinical research to bear on the assessment and management of this important disease. Their comprehensive discussion summarizes the state-of-the-art in diagnosis and treatment, based on the latest understanding of bladder cancer's epidemiology, carcinogenesis, genetics, and tumor markers. Topics of particular interest include the role of genetics and molecular biology in evaluating bladder cancer clinically, the evaluation of the results of systemic treatment in advanced disease, the current status of tumor markers in bladder cancer, and the means for further study of their applicability.

Insightful and evidenced-based, Bladder Cancer: Current Diagnosis and Treatment provides active clinicians and clinical investigators with not only a critical survey of the rapidly expanding research in the area, but also a state-of-the-art tutorial on today's optimal assessment and treatment of bladder cancer.

Klappentext

Michael J. Droller, MD and a panel of experienced clinicians bring their strong background in clinical research to bear on the assessment and management of bladder cancer. Their comprehensive discussion summarizes the state-of-the-art in diagnosis and treatment, based on the latest understanding of bladder cancer's epidemiology, carcinogenesis, and tumor markers. Topics of particular interest include the role of genetics and molecular biology in evaluating bladder cancer clinically, the evaluation of the results of systemic treatment in advanced disease, the current status of tumor markers in bladder cancer, and the means for further study in their applicability. Insightful and evidenced-based, Bladder Cancer: Current Diagnosis and Treatment provides active clinicians and clinical investigators with not only a critical survey of the rapidly expanding research in the area, but also a state-of-the-art tutorial on today's optimal assessment and treatment of bladder cancer.

Inhalt

Demographic and Epidemiologic Aspects of Bladder Cancer Gunnar Steineck Biology and Molecular Aspects of Development and Progression of Bladder Cancer Dan Theodorescu and William A. See Diagnosis of Bladder Cancer Ichabod Jung, Edward M. Messing, and Yves Fradet Diagnostic Imaging in Urothelial Cancer Lynn Ladetsky, Harold Mitty, and Rosaleen B. Parsons Urinary Cytology and its Role in Diagnosis and Monitoring of Urothelial Carcinoma Hans Wijkström, William C. Baker, Arline D. Deitch, and Ralph W. deVere White The Use of Tumor Markers in Bladder Cancer and Current Concepts on Clinical Applicability H. Barton Grossman Pathologic Assessment of Bladder Cancer and Pitfalls in Staging Christer Busch, Debra Hawes, Sonny L. Johansson, and Richard J. Cote Intravesical Chemotherapy in the Treatment of Superficial Bladder Cancer Vincent G. Bird, Mark S. Soloway, and Per-Uno Malmström Use of Intravesical BCG in Treatment of Superficial Bladder Cancer Michael A. O'Donnell Radical Cystectomy and Pelvic Lymphadenectomy in the Treatment of Infiltrative Bladder Cancer John P. Stein, Donald G. Skinner, and James E. Montie Considerations in the Use of Neoadjuvant and Adjunctive Systemic Chemotherapy in Treatment of Invasive Bladder Cancer by Cystectomy Seth P. Lerner and Derek Raghavan Clinical Situations for the Role of Radiation Therapy in the Treatment of Bladder Cancer Mary K. Gospodarowicz, Michael F. Milosevic, Padraiq Warde, and Arthur T. Porter Current Concepts of Urinary Diversion in Men Courtney M.P. Hollowell, Gary D. Steinberg, and Randall G. Rowland Current Concepts of Urinary Diversion in Women Arnulf Stenzl and Georg Bartsch Current Prospects for the Use of Molecular Markers in Treatment of Bladder Cancer by Cystectomy or Bladder-ConservingApproaches Guido Dalbagni, Carlos Cordon-Cardo, and Joel Sheinfeld New Possibilities in Systemic Treatment for Metastatic Bladder Cancer Randall Millikan and Simon J. Hall Statistical Considerations in the Phase II Evaluation of New Therapies Randall Millikan and Peter F. Thall