Behçet's syndrome can reasonably be considered a unique entity among diseases of the immune system for several reasons: It has specific features and, uniquely among the immune system pathologies, represents a link between autoimmune diseases, systemic vasculitis, and autoinflammatory diseases. In addition, it is of interest to a variety of specialists, including immunologists, rheumatologists, dermatologists, and ophthalmologists, and requires a complex multidisciplinary approach. Many aspects need to be considered in a syndrome that presents a wide spectrum of symptoms and for which the therapeutic armamentarium is expanding significantly, with the development of new treatments, not least the so-called biologics. This book offers comprehensive coverage of the disease by some of the world's leading experts in Behçet's syndrome from all the relevant specialties. Epidemiology, genetics, pathogenesis, organ system involvement, differential diagnosis, novel treatments, surgical management,and prognosis are just some of the topics addressed. Behçet's Syndrome: From Pathogenesis to Treatment will be an invaluable reference for a range of practitioners, researchers, and undergraduates or postgraduates interested in immunorheumatology, dermatology, and rare diseases.

Inhalt

Preface 1 Behçet syndrome.- Preface 2 Behçet's syndrome: the role of patient's Associations.- The numbers of Behçet: a rare disease.- Along the Old Silk Road.- Epidemiology of Behçet's syndrome.- Behçet's syndrome according to classical and population genetics.- Infections, autoimmunity and Behçet's syndrome: what liaison.- Pathogenesis of Behçet's syndrome.- Muco-cutaneous involvement in Behçet's syndrome.- Neurological and neuro-psychological manifestation in Behçet's syndrome.- Ocular involvement and Behçet.- Muscle and articular manifestations in Behçet's syndrome.- Cardiovascular issues.- Intestinal Behçet Disease.- Audio vestibular involvement in Behçet's disease.- Pregnancy and Behçet's syndrome.- Pediatric Onset of Behçet's syndrome.- Differential Diagnosis.- Classification and Diagnosis Criteria for Behçet's Disease.- Prognosis and Disease Activity.- Old and New Treatment for Behçet's Disease.- Surgical management of Behçet's Disease.