Animal cell technology is a growing discipline of cell biology which aims to understand the structure, function and behaviour of differentiated animal cells, and especially the development of such abilities as are useful for industrial purposes. These developments range from clonal expansion of differentiated cells with useful abilities, to optimization of cell culture on industrial scale and modulation of the cells' abilities to produce drugs and monoclonal antibodies.
The sixth volume in this series gives a complete review of today's state of the art in Japan, a country where this field is especially well advanced. It will be of interest to cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to animal cell culture, working in the academic environment as well as in (biotechnology or pharmaceutical) industry.

Inhalt

Preface. Symposium 1: Process Validation for Virus Removal/Inactivation in the Bio-Drug Purification Process. Symposium 2: Insect Cell Culture and Baculovirus Expression. Symposium 3: Human Monoclonal Antibodies: Production, Characterization and Clinical Experience. Symposium 4: Transgenic Animals for Production of the Therapeutic Products. Symposium 5: Cell Culture Technology in Tissue and Organ Engineering. Symposium 6: Fish Cell Biotechnology. Mini Symposium I: Novel Bioreactors for Animal Cell Culture. Mini Symposium II: Cell Culture Engineering for High Performance Production of Biologicals. I: Expression of Recombinant Animal Genes in Cultured Cells. II: Establishment and Properties of Functional Cells. III. Serum and Protein-Free Culture. IV: Enhancement of Productivity and Cost Performance for Producing Biochemicals. V: Cell Culture Engineering and High Density Culture. VI: Cell Culture for Assessment of Physiologically Functional Substances. VII: Process Validation on Bio-Drug Purification. VIII: Biological Properties of Proteins Produced by Animal Cells. Author Index. Subject Index.