Anaesthesia Science

Anaesthesia Science presents the scientific foundations upon which the clinical practice of anaesthesia and care of the critically ill are based.

• Written on the basis that basic science underlies the practice of anaesthesia

• Contributors include some of the world's most eminent anaesthesiologists

• Provides coverage on less well appreciated aspects of the subject, such as the microcirculation, multi-organ failure, and the theory of pain

• Thoroughly integrates the clinical practice of anaesthesia with basic sciences, providing all the information needed in one convenient source

• Based on the Fellowship of the Royal College of Anaesthetists (FRCA) syllabus and aimed at trainee anaesthetists preparing for the FRCA, the European Diploma of Anaesthesiology and other equivalent examinations.

Autorentext

Nigel Webster graduated in Medicine from Leeds University in
1977 and obtained his PhD in 1985. He was appointed to the Chair in
Anaesthesia & Intensive Care at the University of Aberdeen, in

1994. Professor Webster has an extensive publication record in
      inflammatory and immune responses in the critically ill. He reviews
      for a number of basic science, anaesthesia and critical care
      journals and is an Editorial Board member for the British Journal
      of Anaesthesia and Critical Care Medicine.

Helen Galley obtained her PhD from the University of
Leeds in 1989. She was appointed to the post of Lecturer in
Anaesthesia & Intensive Care at the University of Aberdeen in
1995 and was promoted to Senior Lecturer in 2000. Dr Galley has
published 60 research papers, 26 reviews/editorials/chapters and
edited 12 books. Her research interests focus on inflammatory and
immune responses in the critically ill. Dr Galley reviews for a
number of basic science, anaesthesia and critical care journals and
is a member of the Board of Management for the British Journal of
Anaesthesia.

Zusammenfassung

Anaesthesia Science presents the scientific foundations upon which the clinical practice of anaesthesia and care of the critically ill are based.

• Written on the basis that basic science underlies the practice of anaesthesia
• Contributors include some of the world's most eminent anaesthesiologists
• Provides coverage on less well appreciated aspects of the subject, such as the microcirculation, multi-organ failure, and the theory of pain
• Thoroughly integrates the clinical practice of anaesthesia with basic sciences, providing all the information needed in one convenient source
• Based on the Fellowship of the Royal College of Anaesthetists (FRCA) syllabus and aimed at trainee anaesthetists preparing for the FRCA, the European Diploma of Anaesthesiology and other equivalent examinations.

Inhalt

Part 1: Pharmacology.

1 Pharmacokinetic principles.

Michel MRF Struys, Alain Kalmar and Peter De Paepe.

2 Pharmacodynamics.

Susan Hill.

3 Pharmacogenomics.

Amr Mahdy.

4 Receptors and second messenger systems.

Thomas Engelhardt.

5 Anaphylaxis.

Michael Rose and Malcolm Fisher.

6 Refl ections on chirality.

Daniel Burke.

7 Ion channels.

George Lees, Leanne Coyne and Karen M. Maddison.

8 Immunosuppression.

Roxanna Bloomfield and David Noble.

9 Mechanisms of anaesthesia: a role for voltage-gated K
channels?.

Peter Århem, Kristoffer Sahlholm and Johanna
Nilsson.

10 Use and abuse of antibiotics.

Jeremy Cohen and Jeffrey Lipman.

Part 2: Physiology.

11 Infl ammation and immunity.

Helen F. Galley.

12 Shock: pathogenesis and pathophysiology.

Anand Kumar.

13 Cellular physiology.

Nigel R. Webster.

14 Acid-base balance: albumin and strong ions.

John A. Kellum.

15 Fluids and electrolytes.

Martin Kuper and Neil Soni.

16 The microcirculation.

Bryce Randalls.

17 Respiratory physiology at the molecular level.

Andrew Lumb.

18 Non-respiratory functions of the lung.

Andrew Lumb and Susan Walwyn.

19 The brain as a site of infl ammation after acute injury.

Jonathan Rhodes and Peter Andrews.

20 Heart failure.

Sze-Yuan Ooi, Christopher Pepper and Stephen Ball.

21 The hormonal and metabolic response to anaesthesia, surgery
and trauma.

Grainne Nicholson and George M. Hall.

22 Temperature regulation.

Anita Holdcroft.

23 Theories of pain.

Lesley Colvin.

24 Neuromuscular transmission and function.

Andrew D. Axon and Jennifer M. Hunter.

Part 3: Clinical measurement.

25 Magnetic resonance imaging.

Fiona J. Gilbert and Thomas W. Redpath.

26 Nanotechnology.

The Nanotechnology Study Group, University of
Aberdeen.

27 Assessment of the cardiovascular system.

Charles S. Reilly.

28 Assessment of respiratory function.

Stuart Murdoch.

29 Monitoring the depth of anaesthesia.

Praveen Kalia.

30 Research study design.

John Robert Sneyd