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Preface. List of Contributors. I: Lipoxygenases and Leukotriene Biosynthesis. 1. Phosphorylation and Activation of 5-Lipoxygenase by P38 Kinase-Activated MAPKAP Kinases; O. Werz, et al. 2. 5-Lipoxygenase and the Nucleus: Where, When, How, and Why?; M. Peters-Golden, T.G. Brock. 3. Calcium Binding Site of 5-Lipoxygenase; T. Hammarberg, et al. 4. Regulation of Cellular 50Lipoxygenase Activity by Glutathione Peroxidases; D. Schumann, et al. 5. Novel Aspects Related to Biosynthesis and Biological Actions of Hepoxilins: Interrelationship with Phospholipid Hydro-Peroxide Glutathione Peroxidase (PHGPx); P. Shankaranarayanan, et al. 6. Transcriptional Regulation of the Human Leukotriene C4 Synthase Promoter; J.-L. Zhao, et al. 7. Localization and Translocation of Enzymes Involved in Leukotriene Biosynthesis; Y. Ide, et al. II: Cyclooxygenases and Prostaglandin Biosynthesis. 8. Regulation of COX-2 Expression in Fibroblasts, Osteoblasts, Mast Cells, and Macrophages; H.R. Herschman, et al. 9. Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase-2: A Novel Mechanism for NSAID and N-3 PUFA Therapeutic Actions; C.N. Serhan, et al. 10. Substrate Interactions in the Cyclooxygenase-1 Active Site; E.D. Thuresson, et al. 11. Mutation of the Human Prostacyclin Synthase Gene; T. Nakayama, et al. 12. Structure and Function of Two Distinct Types of Prostaglandin D Synthase; Y. Urade, O. Hayaishi. 13. Roles of Prostaglandin F Synthase; K. Watanabe, et al. 14. Differential Effects of Nitric Oxide on Cyclooxygenase 1 and 2 Activities in Cultured Cells; S.-I. Murota, et al. III: Phospholipase A2. 15. On the Functional Diversity of Secreted Phospholipases A2: Cloning of Novel Mammalian and HIV-1 Antiviral Properties; G. Lambeau, et al. 16. Regulation of Cytosolic Phospholipase A2 by Phosphorylation; M.H. Gelb, et al. IV: Cytochrome P450 Archidonate Metabolites. 17. Synthesis and Function of 20-Hydroxyeicosatetraenoic Acid in the Kidney; M.L. Schwartzman, et al. V: Receptors. 18. Altered Bronchodilation and Pulmonary Inflammation in Prostanoid EP2 Receptor Knockout Mice; F. Nantel, et al. 19. Induction of Prostaglandin I2 Receptor in Murine Osteoblastic Cell; K. Yamamoto, et al. 20. BLT2, a Second Leukotriene B4 Receptor; T. Yokomizo, et al. 21. Upregulation of Cysteinyl-Leukotriene 1 Receptor Expression by Interleukin-5 in Human Leukocytes; M. Rola-Pleszczynski, et al. 22. Physiological and Pathophysiological Roles of Prostanoids; Lessons from Receptor-Knockout Mice for Clinical Applications; S. Narumiya. 23. Multiple G-Protein Coupling of Chimeric Prostacyclin/Prostaglandin D2 Receptors; H. Wise, K.B.S. Chow. VI: Eicosanoids and Neuroscience. 24. An Unusual Nicotinic Acetylcholine Receptor Activates the 8-Lipoxygenase Pathway in Aplysia Neurons; S.J. Feinmark, et al. VII: Cardiovascular System. 25. Neutrophil-Endothelial Cell Interaction: A Multidirectional Cross-Talk in Leukotriene Generation; G.C.