This book constitutes the refereed proceedings of the Second Brazilian Symposium on Bioinformatics, BSB 2007, held in Angra dos Reis, Brazil, in August 2007, co-located with IWGD 2007, the International Workshop on Genomic Databases. The papers address a broad range of current topics in computational biology and bioinformatics.

Inhalt

Selected Articles.- Automating Molecular Docking with Explicit Receptor Flexibility Using Scientific Workflows.- Gene Set Enrichment Analysis Using Non-parametric Scores.- Comparison of Simple Encoding Schemes in GA's for the Motif Finding Problem: Preliminary Results.- Multi-Objective Clustering Ensemble with Prior Knowledge.- Biological Sequence Comparison Application in Heterogeneous Environments with Dynamic Programming Algorithms.- New EST Trimming Procedure Applied to SUCEST Sequences.- A Method for Inferring Biological Functions Using Homologous Genes Among Three Genomes.- Validating Gene Clusterings by Selecting Informative Gene Ontology Terms with Mutual Information.- An Optimized Distance Function for Comparison of Protein Binding Sites.- Comparing RNA Structures: Towards an Intermediate Model Between the Edit and the Lapcs Problems.- Evolving Phylogenetic Trees: A Multiobjective Approach.- Comparing Several Approaches for Hierarchical Classification of Proteins with Decision Trees.- High Efficiency on Prediction of Translation Initiation Site (TIS) of RefSeq Sequences.- Extended Abstracts.- Outlining a Strategy for Screening Non-coding RNAs on a Transcriptome Through Support Vector Machines.- Mapping Contigs onto Reference Genomes.- Molecular Dynamics Simulations of Cruzipains 1 and 2 at Different Temperatures.- Genetic Algorithm for Finding Multiple Low Energy Conformations of Poly Alanine Sequences Under an Atomistic Protein Model.- Cellular Fingerprints: A Novel Concept for the Integration of Experimental Data and Compound-Target-Pathway Relations (Extended Abstract).- Identification of the Putative Class 3 R Genes in Coffea arabica from CafEST Database.