Advances in Bioinformatics and Computational Biology

This book constitutes the refereed proceedings of the Brazilian Symposium on Bioinformatics, BSB 2020, held in São Paulo, Brazil, in November 2020. Due to COVID-19 pandemic the conference was held virtually The 20 revised full papers and 5 short papers were carefully reviewed and selected from 45 submissions. The papers address a broad range of current topics in computational biology and bioinformatics.

Inhalt

A Classification of de Bruijn Graph approaches for De Novo Fragment Assembly.- Redundancy Treatment of NGS Contigs in Microbial Genome Finishing with Hashing-Based Approach.- Efficient Out-of-core Contig Generation.- In silico Pathogenomic Analysis of Corynebacterium pseudotuberculosis biovar ovis.- Assessing the sex-related genomic composition diffeerence using a K-mer-based approach: a case of study in Arapaima gigas (Pirarucu) .- COVID-19 X-ray Image Diagnostic with Deep Neural Networks.- Classification of Musculoskeletal Abnormalities with Convolutional Neural Networks.- Combining mutation and gene network data in a machine learning approach for false-positive cancer driver gene discovery.- Unraveling the role of Nanobodies Tetrad on their Folding and Stability Assisted by Machine and Deep Learning Algorithms.- Experiencing DfAnalyzer for Runtime Analysis of Phylogenomic Dataows.- Sorting by Reversals and Transpositions with Proportion Restriction.- Heuristics for Breakpoint Graph Decomposition with Applications in Genome Rearrangement Problems.- Center Genome With Respect to the Rank Distance.- ImTeNet: Image-Text Classification Network for Abnormality Detection and Automatic Reporting on Musculoskeletal Radiographs.- A scientometric overview of bioinformatics tools in the Pseudomonas putida genome study.- Polysome-seq as a Measure of Translational Profile from Deoxyhypusine Synthase Mutant in Saccharomyces cerevisiae.- Anti-CD3 stimulated T cell transcriptome reveals novel ncRNAs and correlates with a suppressive profile.- A simplified complex network-based approach to mRNA and ncRNA transcript classification.- A systems biology driven approach to map the EP300 interactors using comprehensive protein interaction network.- Analyzing switch regions of human Rab10 by molecular dynamics simulations.- Importance of meta-analysis in studies involving plant responses to climate change in Brazil.- A brief history of Bioinformatics told by data visualization.- Computational Simulations for Cyclizations Catalyzed by Plant Monoterpene Synthases.- Oncogenic signaling pathways in Mucopolysaccharidoses.- Natural products as potential inhibitors for SARS-CoV-2 papain-like protease: an in silico study.