This book provides a comprehensive exploration of colorectal cancer (CRC), covering its development, cellular and molecular pathologies, diagnostic methods, treatment modalities, challenges, and future research directions. The introductory chapters provide foundational aspects of CRC, its historical evolution, prevalent symptoms, and underlying causes. This book presents the pathology of CRC, delving into microscopic analysis techniques, and covers the classification and various stages of CRC. Additionally, this book examines the cellular and molecular aspects of the disease, unraveling the intricate signaling pathways involved, and shedding light on the genetic and epigenetic factors that contribute to its development and progression. This book further explores tools and techniques utilized in clinical practice, including cellular, molecular, and genetic testing methods. It examines various treatment modalities for CRC, including chemotherapy, radiation therapy, and immunotherapy, highlighting their associated advantages and disadvantages. Toward the end, this book highlights innovative trends and advancements in CRC diagnosis and treatment, including the transformative role of machine learning, artificial intelligence, stem cells, and nano drug delivery systems. This book serves as a vital resource for the latest information for researchers, cancer research students, and oncologists.

Key Features

• Reviews cellular and molecular pathologies, diagnostic methods, and treatment modalities of CRC
• Discusses diagnostic methods and treatment strategies, including chemotherapy, radiation therapy, and immunotherapy
• Highlights the role of machine learning, artificial intelligence, stem cells, and nano drug delivery systems in CRC diagnosis and treatment
• Examines the genetic and epigenetic factors that contribute to the development and progression of CRC

• Delves into the cellular and molecular aspects of CRC, elucidating complex signaling pathways involved in disease initiation and progression

  Autorentext

  Firdos Alam Khan is a Professor at the Department of Stem Cell Biology, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. He has received his Ph.D. degree in Zoology with a specialization in Neuroscience from Nagpur University, India. Professor Khan has been involved in teaching various courses such as Biochemistry and Cell Physiology, Stem Cell Biology and Regenerative Medicine, Cell Biology, Pharmacology, Business of Biotechnology, Biomedicine, Cell & Tissue Engineering, and Bioethics & IPR to undergraduate and postgraduate students. Professor Khan was associated with the Manipal Academy of Higher Education, Dubai Campus, United Arab Emirates where he was a Professor and Chairperson, School of Life Sciences, and served as Chairman of the Research & Development Program. Professor Khan did the first postdoctoral fellowship from the National Centre for Biological Sciences (NCBS), Bangalore, India, and a second postdoctoral fellowship from the Massachusetts Institute of Technology (MIT), Cambridge, USA. Professor Khan has also worked with Reliance Life Sciences as a Research Scientist in the Stem Cell Research Laboratory. Professor Khan has been granted 17 US patents. Professor Khan has authored and edited 9 books which are published by international publishers. Professor Khan is a recognized reviewer of Scientific Report, Nanomedicine, Pharmaceutics, Pharmaceuticals, Nanomedicine: Nanomedicine, Biology, and Medicine, International Journal of Nanomedicine, Microscopy and Microanalysis, IET Nanobiotechnology, Polymers, Drug Design, Development and Therapy, Current Pharmaceutical Biotechnology, Tissue Engineering Part A, Journal of Bimolecular Structure and Dynamics, Nanotechnology Reviews, 3-Biotechnology, Molecules, Biotechnology Letters, Journal of Nanostructure Chemistry, Pharmaceutical Patent Analysis, World Journal of Surgical Oncology, NanoExpress, Advances in Natural Sciences: Nanoscience and Nanotechnology and Cancers. He has published more than 145 research publications. Professor Khan is a Fellow of the Royal Society of Biology (RSB), UK, and also a member of the Sigma Xi Honor Society, USA (MIT Chapter). Currently, Professor Khan is studying the role of different types of nanomaterials and biomaterials in regenerative medicine and cancer treatment.