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Pharmaceutical Powder Compaction Technology

  • Livre Relié
  • 358 Nombre de pages
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"Revised to reflect modern pharmaceutical compacting techniques, this Second Edition guides pharmaceutical engineers, formulation ... Lire la suite
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Description

"Revised to reflect modern pharmaceutical compacting techniques, this Second Edition guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. Compaction of powder constituents both active ingredient and excipients is examined to ensure consistent and reproducible disintegration and dispersion profiles. This unique reference covers: the physical structure of pharmaceutical compacts bonding phenomena that occur during powder compaction compression mechanisms of pharmaceutical particles theories and basic principles of powder compaction New topics include: compaction data analysis techniques the migration of powder constituents into commercialmanufacture instrumentation for compaction compaction functionality testing, which is likely to become a USP requirement design space for compaction metrics required for scalability in tablet compression interactive compaction and preformulation databasefor commonly used excipients"--Provided by publisher.

Résumé
Compaction of powder constituentsboth active ingredient and excipientsis examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of Pharmaceutical Powder Compaction Technology guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. This unique reference covers: The physical structure of pharmaceutical compacts Bonding phenomena that occur during powder compaction Compression mechanisms of pharmaceutical particles Theories and basic principles of powder compaction New topics include: Compaction data analysis techniques The migration of powder constituents into commercial manufacture Instrumentation for compaction Compaction functionality testing, which is likely to become a USP requirement Design space for compaction Metrics required for scalability in tablet compression Interactive compaction and preformulation database for commonly used excipients

Contenu
THEORY OF COMPACTIONIntermolecular Bonding Forces: where materials and process come together Graham BucktonCOMPACTION DATA ANALYSIS TECHNIQUESViscoelastic ModelsSusan K. LumApplication of Percolation Theory and Fractal Geometry to Tablet CompactionHans Leuenberger, Maxim Puchkov, Ruth Leu-Marseiler, Jean-Daniel Bonny, Michael N. LeuenbergerPost Compaction Data Analysis TechniquesGary BubbINTRUMENTATION AND EQUIPMENT IN COMPACTIONTablet Press Instrumentation in the Research and Development EnvironmentGary BubbAdvanced Compaction Research Equipment: Compaction SimulatorsColleen Ruegger, Metin ÇelikCompactability Functionality TestEay OkutgenROLE OF COMPACTION IN THE FORMULATION AND PROCESS DEVELOPMENT OF TABLETTINGCompaction Properties of Directly Compressible MaterialsGerad K. Bolhuis, Hans de WaardLubrication Issues in Direct CompactionGerad K. Bolhuis, Arne W. Hölzer Crystal Engineering and Particle Design for the Powder Compaction ProcessAnant Paradka, Peter YorkCompaction of Combination ProductsCarl T. Allenspach, Erika A. ZannouQuality by Design and Compression Chris Balducci, Rosario LoBrutto, Alan Royce, James Cheney, Dong Xiang, Olivia Darmuzey, Hedinn ValthorssonExpert Systems and Their Use in Pharmaceutical ApplicationsMetin ÇelikPress-To-Press Scalability and Transitioning FactorsGary Bubb

Informations sur le produit

Titre: Pharmaceutical Powder Compaction Technology
Sous-titre: 2nd Edition
Éditeur:
Code EAN: 9781420089172
ISBN: 978-1-4200-8917-2
Format: Livre Relié
Editeur: Taylor and Francis
Genre: Branches
nombre de pages: 358
Poids: 862g
Taille: H254mm x B178mm
Année: 2011
Auflage: 2. A.