Clinical Reproductive Science

The comprehensive and authoritative guide to clinical reproductive science

The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advance in clinical embryology. The author - a noted expert in the field - focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation.

Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The author includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource:

• Offers an accessible guide to the most current research and techniques to the science of clinical reproduction
• Covers the fundamental elements of reproductive science
• Includes information on male and the female reproductive basics - everything from sexual differentiation to foetal development and parturition
• Explores the long-term health of children conceived through IVF
• Contains the newest developments in assisted reproductive technology

Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.

Auteur
About the Editor MICHAEL CARROLL, Senior Lecturer in Reproductive Science, School of Healthcare Science, Manchester Metropolitan University, U

Texte du rabat

The comprehensive and authoritative guide to clinical reproductive science The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advance in clinical embryology. The author - a noted expert in the field - focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation. Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The author includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource: Offers an accessible guide to the most current research and techniques to the science of clinical reproduction Covers the fundamental elements of reproductive science Includes information on male and the female reproductive basics - everything from sexual differentiation to foetal development and parturition Explores the long-term health of children conceived through IVF * Contains the newest developments in assisted reproductive technology Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.

Contenu

List of Contributors xi About the Editor xv Preface xvii Acknowledgements xix About the Companion Website xxi Section One Reproductive Science: Fundamentals of Human Reproductive Biology 1 1 Sexual Differentiation, Gonadal Development, and Development of the External Genitalia: A Review of The Regulation of Sexual Differentiation 3 Rebecca M. Perrett 2 Male and Female Reproductive Anatomy 35 Sara Sulaiman and James Coey 3 Fundamentals of Reproductive Endocrinology 45 Derrick Ebot, Haider Hilal, Michael Carroll, and James Coey 4 The Ovaries, Oocytes, and Folliculogenesis 57 Jacques Gilloteaux and James Coey 5 The Human Spermatozoa 65 Allan Pacey and Katrina Williams 6 The Biology of Fertilization 75 Michael Carroll 7 Human Embryo Development: From Zygote Stage to Peri-Implantation Blastocyst 93 Stéphane Berneau and Michael Carroll 8 The Female Reproductive Tract and Early Embryo Development: A Question of Supply and Demand 99 Henry J. Leese and Daniel R. Brison Section Two Clinical Reproductive Science: Causes of Male and Female Infertility 109 9 Disorders of Male Reproductive Endocrinology 111 Michael Carroll 10 Disorders of Female Reproductive Endocrinology 125 Mahshid Nickkho-Amiry and Cheryl T. Fitzgerald 11 Oocyte Aneuploidy and the Maternal Age Effect 133 Mary Herbert 12 Female Reproductive Pathology: Peritoneal, Uterine, and Fallopian Tube Pathologies 147 Kenneth Ma Kin Yue, Rosa Trigas, and Edmond Edi-Osagie 13 Pathologies of the Male Reproductive Tract 159 Aarush Sajjad, Muhammad A. Akhtar, and Yasmin Sajjad 14 The Impact of Infections on Reproduction and Fertility 177 Val Edwards Jones 15 Nutrition, Fetal Health, and Pregnancy 189 Emma Derbyshire 16 The Embryonic Environment and Developmental Origins of Health 195 Tom P. Fleming and Congshan Sun 17 Lifestyle and Environmental Impacts on Fertility 205 Ana-Maria Tomova and Michael Carroll Section Three Clinical Reproductive Science In Practice: IVF and Assisted Reproductive Technologies 215 18 Assessing the Infertile Couple 217 Narmada Katakam, Ruth Arnesen, Caroline Watkins, Bert Stewart, and Luciano G. Nardo 19 Ovarian Stimulation Protocols 231 Nikolaos Tsampras and Cheryl T. Fitzgerald 20 Oocyte Retrieval Techniques and Culture of Oocytes 241 Dawn Yell 21 Sperm Preparation: Strategy and Methodology 251 Stephen Harbottle 22 Diagnostic Semen Analysis: Uncertainty, Clinical Value, and Recent Advances 265 Mathew Tomlinson 23 Surgical Sperm Retrieval 279 Muhammad A. Akhtar, Elizabeth Hester, Solmaz Gul Sajjad, and Yasmin Sajjad 24 In Vitro Fertilization and Intracytoplasmic Sperm Injection 291 Bryan Woodward 25 Morphological Assessment of Embryos in Culture 303 J. Diane Critchlow 26 In Vitro Culture of Gametes and Embryos - The Culture Medium 317 Robbie Kerr 27 Incubators in the Assisted Reproductive Technology Laboratory 333 Louise Hyslop 28 Embryo Transfer Techniques and Improving Embryo Implantation Rates 341 Rachel Cutting 29 Cryopreservation of Gametes and Embryos 351 Tope Adeniyi 30 Preimplantation Genetic Diagnosis and Screening 371 Colleen Lynch and Brendan Ball 31 Long-Term Follow-Up of Children Conceived Through In Vitro Fertilization 385 Omar Abdel-Mannan and Alastair G. Sutcliffe Index 393