Organic Chemistry

Praise for the first edition: "Summing Up: Recommended"CHOICE, June 2011 "After a brief historical overview and a chapter on the acid-base theme, the standard programme is rolled out, although with an almost unbroken emphasis on the acid-base approach the body of the text is easy to read, and the well chosen questions following almost every paragraph encourage the reader to start digesting the provided information immediately."Martina Lahmann in Education in Chemistry, May 2011 "This new book is designed to provide a new approach to teaching organic chemistry, to understand the relationships between functional group via an acid-base theme. In 28 chapters the author provides a mechanistic approach to teaching organic chemistry, focusing on fundamental principles rather than a comprehensive accumulation of factual knowledge."Organic Process Research, 2011

Auteur

Michael B. Smith, University of Connecticut, Storrs, USA

Texte du rabat

Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid base concepts, this book provides a framework for understanding the subject that goes beyond mere memorization. Using several techniques to develop a relational understanding, it helps students gain a more concrete understanding of the most fundamental concepts in organic chemistry that are applied to industry, biological chemistry, biochemistry, molecular biology, and pharmacy.

Contenu

Introduction. Why Is an Acid Base Theme Important? Bonding. Alkanes, Isomers, and an Introduction to Nomenclature. Functional Groups. Acids, Bases, Nucleophiles, and Electrophiles. Chemical Reactions, Bond Energy, and Kinetics. Rotamers and Conformation. Stereoisomers: Chirality, Enantiomers, and Diastereomers. Acid Base Reactions of -Bonds: Addition Reactions. Nucleophiles: Lewis Base-Like Reactions at sp3 Carbon. Bases-Induced Elimination Reactions. Substitution and Elimination Reactions Can Compete. Spectroscopic Methods of Identification. Organic Molecules That Contain Alkali Metals or Transition Metals (Organometallics). Carbonyl Compounds: Structure, Nomenclature, Reactivity. Oxidation. Reactions of Aldehydes and Ketones. Reduction. Carboxylic Acid Derivatives and Acyl Substitution. Aromatic Compounds and Benzene Derivatives. Enolate Anions: Acyl Addition and Acyl Substitution. Difunctional Molecules: Dienes and Conjugated Carbonyl Compounds. Difunctional Molecules: Pericyclic Reactions. Retrosynthesis and Synthesis. Heteroaromatic Compounds. Multifunctional Compounds: Amino Acids and Peptides. Multifunctional Compounds: Carbohydrates.