Cellular and Molecular Neurophysiology

Auteur

Constance Hammond is an INSERM director of research at the Mediterranean Institute of Neurobiology. A renowned Parkinson's disease investigator, in 2012 she became a Chevalier of the Légion d'Honneur in recognition for her services to scientific communication. Studying biology at the University of Pierre and Marie Curie and the Ecole Normale Supérieure in Paris she completed her thesis in neurosciences at the Marey Institute in Paris, directed by Prof. D. Albe-Fessard. Guided by her curiosity and her constant desire to learn, she changed lab and research domains several times. With the knowledge of other systems and the mastering of other techniques she finally came back to her first and preferred subject of research; the role of the subthalamic nucleus in the basal ganglia system in health and Parkinson's disease.

Texte du rabat

Cellular and Molecular Neurophysiology, Fifth Edition is the only up-to-date textbook on the market that focuses on the molecular and cellular physiology of neurons and synapses. Hypothesis-driven rather than a dry presentation of the facts, the book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in graduate-level courses on the topic alike. This new edition explains the molecular properties and functions of excitable cells in detail and teaches students how to construct and conduct intelligent research experiments. The content is firmly based on numerous experiments performed by top experts in the field.

The new edition contains new chapters on recording neuronal activity, iconotrophic and metabotropic receptors for sensory transduction, and a section containing exercises for further learning. This book will be a useful resource for neurophysiologists, neurobiologists, neurologists, and students taking graduate-level courses on neurophysiology.

Contenu

1. Neurons
   
   2. Neuron-glial cell cooperation
   3. Ionic gradients
   4. How to record neuronal activity (+ films)
   5. The voltage-gated channels of Na action potentials
   6. The voltage-gated channels of Ca action potentials
   7. The chemical synapses
   8. Neurotransmitter release (+ animations)
   9. The ionotropic nicotinic acetylcholine receptor
   10. The ionotropic GABA-A receptor (+ films)
   11. The ionotropic glutamate receptors (+ films)
   12. The ionotropic receptors of sensory transduction : example of TRP channels
   13. The metabotropic GABAB receptors
   14. The metabotropic glutamate receptors
   15. The metabotropic receptors for sensory transduction : example of olfatory receptors
   16. Somato-dendritic processing of postsynaptic potentials I
   17. Subliminal voltage-gated currents of the somato dendritic membrane
   18. Somato-dendritic processing of postsynaptic potentials II
   19. Somato-dendritic processing of postsynaptic potentials III
   20. Firing patterns of neurons
   21. Synaptic plasticity
   22. The development of the hippocampal network
   23. The adult hippocampal network
   24. Exercises