Purines, Pyrimidines and Nucleotides

Purines, Pyrimidines and Nucleotides and the Chemistry of Nucleic Acids serves as an introduction to the basic chemistry of purines and pyrimidines and their derivatives.
The textbook focuses on topics that provide information on the nature and properties of purines and pyrimidines and nucleic acid. Chapters are devoted to topics on the general chemistry of purines and pyrimidines; synthesis of purines and pyrimidines; and the structure, synthesis, and mechanism of nucleosides, nucleotides, and nucleic acids.
Biochemists, chemists, molecular biologists, and senior undergraduates taking courses in heterocyclic and natural products chemistry will find the book very useful.

Contenu

Author's Preface
Introduction
I. General Chemistry Of Purines And Pyrimidines

1. General Character of Purines and Pyrimidines
2. Substitution by Electrophilic Reagents
3. Substitution by Nucleophilic Reagents
4. Rearrangements
5. Reduction
6. Addition Reactions
7. Acylation and Alkylation
8. Oxidation
   References
   II. Synthesis of Purines and Pyrimidines
9. Pyrimidines
10. Purines
    References
    III. Nucleosides
11. Structure
12. Synthesis
13. Mechanism and Stereochemistry of Nucleoside Synthesis
14. Analogues
    References
    IV. Nugleotides
15. Ribonucleotides
16. Deoxyribonucleotides
17. Other Nucleotides
18. Biosynthesis of Mononucleotides
    References
    V. Nucleic Acids
19. Structure of DNA
20. Structure of RNA
21. Biosynthesis of Nucleic Acids
    References
    Index