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This book provides detailed reviews of a range of nanostructures used in the construction of biosensors as well as the applications of these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields
Biological sensing is a fundamental tool for understanding living systems, but also finds practical application in medicine, drug discovery, process control, food safety, environmental monitoring, defense, and personal security. Moreover, a deeper understanding of the bio/electronic interface leads us towards new horizons in areas such as bionics, power generation, and computing. Advances in telecommunications, expert systems, and distributed diagnostics prompt us to question the current ways we deliver healthcare, while robust industrial sensors enable new paradigms in R&D and production.
Despite these advances, there is a glaring absence of suitably robust and convenient sensors for body chemistries. This book examines some of the emerging technologies that are fueling scientific discovery and underpinning new products to enhance the length and quality of our lives.
The 14 chapters written by leading experts cover such topics as:
ZnO and graphene microelectrode applications in biosensing
Assembly of polymers/metal nanoparticles
Gold nanoparticle-based electrochemical biosensors
Impedimetric DNA sensing employing nanomaterials
Graphene and carbon nanotube-based biosensors
Computational nanochemistry study of the BFPF green fluorescent protein chromophore
Biosynthesis of metal nanoparticles
Bioconjugated-nanoporous gold films in electrochemical biosensors
The combination of molecular imprinting and nanotechnology
Principles and properties of multiferroics and ceramics
Auteur
Ashutosh Tiwari is an Associate Professor at the
Biosensors and Bioelectronics Centre, Linköping University,
Sweden; Editor-in-Chief, Advanced Materials Letters;
Secretary General, International Association of Advanced Materials;
a materials chemist and also a docent in applied physics at
Linköping University, Sweden. He has published more than 350
articles, patents, and conference proceedings in the field of
materials science and technology and has edited/authored more than
fifteen books on the advanced state-of-the-art of materials
science. He is a founding member of the Advanced Materials World
Congress and the Indian Materials Congress.
Anthony P.F. Turner is currently Head of Division
FM-Linköping University's new Centre for Biosensors and
Bioelectronics. His previous thirty-five year academic career in
the UK culminated in the positions of Principal (Rector) of
Cranfield University and Distinguished Professor of Biotechnology.
Professor Turner has more than 600 publications and patents in the
field of biosensors and biomimetic sensors and is best known for
his role in the development of glucose sensors for home-use by
people with diabetes. He published the first textbook on biosensors
in 1987 and is Editor-In-Chief of the principal journal in his
field, Biosensors & Bioelectronics, which he co-founded
in 1985.
Contenu
**Preface xv
Part 1: New Materials and Methods 1
1 ZnO and Graphene Microelectrode Applications in Biosensing 3
*Susana Campuzano, María Pedrero, Georgia-Paraskevi Nikoleli, José M. Pingarron, Dimitrios P. Nikolelis, Nikolaos Tzamtzis and Vasillios N. Psychoyios
1.1 Biosensors Based on Nanostructured Materials 4
1.2 Graphene Nanomaterials Used in ElectrochemicalBiosensor Fabrication 5
1.3 ZnO Nanostructures Used in the Fabrication of Electrochemical Biosensors 7
1.4 Miniaturized Graphene and ZnO Nanostructured Electrochemical Biosensors for Food and Clinical Applications 10
1.5 Conclusions and Future Prospects 30
Acknowledgements 32
References 32
**2 Assembly of Polymers/Metal Nanoparticles and Their Applications as Medical Devices 37
*Magdalena Stevanovic
2.1 Introduction 38
2.2 Platinum Nanoparticles 40
2.3 Gold Nanoparticles 41
2.4 Silver Nanoparticles 44
2.5 Assembly of Polymers/Silver Nanoparticles 45
2.6 Conclusion 51
Acknowledgements 51
References 52
**3 Gold Nanoparticle-Based Electrochemical Biosensors for Medical Applications 63
Ülkü *Anik
3.1 Introduction 63
3.2 Gold Nanoparticles 64
3.3 Conclusion 76
References 76
**4 Impedimetric DNA Biosensors Based on Nanomaterials 81
*Manel del Valle and Alessandra Bonanni
4.1 Introduction 82
4.2 Electrochemical Impedance Spectroscopy for Genosensing 85
4.3 Nanostructured Carbon Used in Impedimetric Genosensors 91
4.4 Nanostructured Gold Used in Impedimetric Genosensors 97
4.5 Quantum Dots for Impedimetric Genosensing 100
4.6 Impedimetric Genosensors for Point-of-Care Diagnosis 101
4.7 Conclusions (Past, Present and Future Perspectives) 102
Acknowledgements 104
References 104
**5 Graphene: Insights of its Application in Electrochemical Biosensors for Environmental Monitoring 111
*G.A. Álvarez-Romero, G. Alarcon-Angeles and A. Merkoçi
5.1 Introduction 112
5.2 Environmental Applications of Graphene-based Biosensors 117
5.3 Conclusions and Perspectives 133
References 134
**6 Functional Nanomaterials for Multifarious Nanomedicine 141
*Ravindra P. Singh, Jeong-Woo Choi, Ashutosh Tiwari and Avinash Chand Pandey
6.1 Introduction 142
6.2 Nanoparticle Coatings 145
6.3 Cyclic Peptides 147
6.4 Dendrimers 149
6.5 Fullerenes/Carbon Nanotubes/Graphene 156
6.6 Functional Drug Carriers 157 6.7 MRI Scanning Nanoparticles 162
6.8 Nanoemulsions 165
6.9 Nanofibers 166
6.10 Nanoshells 169
6.11 Quantum Dots 171
6.12 Nanoimaging 179
6.13 Inorganic Nanoparticles 180
6.14 Conclusions 182
Acknowledgement 183
References 183
**Part 2: Principals and Prospective 199
7 Computational Nanochemistry Study of the Molecular Structure, Spectra and Chemical Reactivity Properties of the BFPF Green Fluorescent Protein Chromophore 201
*Daniel Glossman-Mitnik
7.1 Introduction 201
7.2 Theory and Computational Details 202
7.3 Results and Discussion 206
7.4 Conclusions 233
Acknowledgements 234
References 234
**8 Biosynthesis of etal Nanoparticles and Their Applications 239
*Meryam Sardar, Abhijeet Mishra and Ra...