Tumor Microenvironments in Organs

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more.

Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Provides a comprehensive overview of the state-of-the-art research on the tumor microenvironment in over thirty human organs, including the thyroid, bladder, intestine, tongue, and more Illustrates how cancer cells in different human tissues are affected by different components of the tumor microenvironment Identifies specific components in the tumor microenvironment for each tissue type that may become specific targets for cancer treatment

Auteur

Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Résumé

Contenu

The intestinal tumour microenvironment.- Gastric Tumor Microenvironment.- Parathyroid tumor microenvironment.- Microenvironment in Cardiac Tumor Development: What Lies Beyond the Event Horizon?.- The roles of bone marrow-resident cells as a microenvironment for bone metastasis.- Adipose tumor microenvironment.- Appendix Tumor Microenvironment.- Spinal cord tumor microenvironment.- Cancer stem cell niche and immune-active tumor microenvironment in testicular germ cell tumors.- Tumor microenvironment in skin carcinogenesis.- Index.