The Neuroscience of Deep Brain Stimulation: Research and Clinical Applications

Texte du rabat

Deep Brain Stimulation (DBS) is an established and successful treatment options for patients with movement disorders, including Parkinson's disease, dystonia, and some psychiatric conditions. Neuroscience of Deep Brain Stimulation: Research and Clinical Applications, begins by introducing readers to the foundational research and historical background of DBS, including developmental experimental models for movement and psychiatric disorders. The second section reviews various clinical applications including numerous and in-depth case studies. The final section identifies the mechanisms of action behind DBS, including cellular, metabolic and neurochemical mechanisms. Internationally contributed, this book will become the essential guide for anyone in the field of DBS.

Contenu

Part 1: Bench 1. The quest for a target and the beginning of the DBS-story 2. Early clinical application 3. Development of experimental models for movements disorders 4. Development of experimental models for psychiatric disorders Part 2: Science behind the clinical application 5. Parkinson s disease 6. Dystonia 7. Essential tremor 8. Epilepsy 9. OCD 10. Tourette Syndrome 11. Depression 12. Alzheimer s disease 13. Other indications Part 3: Mechanisms of action 14. Neurophysiological mechanisms 15. Cellular mechanisms 16. Metabolic mechanisms 17. Neurochemical mechanisms 18. Mechanisms investigated by imaging Part 4. Future/perspectives