Synthetic Strategies in Carbohydrate Chemistry

Texte du rabat

Synthetic Strategies in Carbohydrate Chemistry covers carbohydrate synthesis and its widespread application in various disciplines including catalysis. Basic and advanced aspects of carbohydrates are covered, starting with a brief introduction, followed by protection-deprotection strategies in carbohydrate chemistry, glycosidic bond formation methodology and their impact in oligosaccharide synthesis. Recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides and C-glycosides, Intramolecular Aglycon Delivery (IAD), and carbohydrate modification are discussed, as well as stereoelectronic factors that control the chemical and biochemical behavior of carbohydrates in living cells. Diverse applications of synthetic carbohydrate chemistry are covered, including sugar-based chiral catalyst in stereoselective synthesis, sugar-based ionic liquids, one-pot tandem reactions in carbohydrates, total synthesis of glycoconjugated natural products, impact of sugar in drug discovery and development, vaccine development, and glycoengineering. This reference is essential reading for researchers working in synthetic carbohydrate chemistry and biochemistry, and will be useful to those working in total synthesis, novel synthetic methodology, catalysis, polymer science, glycobiology, medicinal chemistry, and process development chemistry as well.

Contenu

1. Concepts on Protection-Deprotection strategies in Carbohydrate Chemistry
   
   2. Recent Approaches in Glycosylation Methodology and their impact in Oligosaccharide Synthesis
   3. One-Pot Automated Glycosylation Strategies in Oligosaccharide Synthesis
   4. Intramolecular Glycosylation: Opportunities and Challenges
   5. Synthesis, Significance and Scope of Thio-glycosides
   6. Recent Developments on Synthesis of C-glycosylated Molecules
   7. Recent Approaches in the Synthesis of Diverse Imino Sugars
   8. Functionalized cyclohexanes from simple carbohydrate derivatives
   9. Recent Development on Diversified Sialic acid Modification
   10. Glycal Chemistry and their Scope in Glycohybrid Synthesis
   11. Synthetic Approaches for diverse Sugar-based Ligands and Organocatalysts
   12. Recent approaches for carbohydrate-containing Macrocycles
   13. Enzymes in Synthesis of diverse Carbohydrate-containing Molecules
   14. Processing of Lignocellulosic Biomass into Value Added Products
   15. Recent Synthetic Approaches for Glycopeptides and Glycopolymers
   16. Common Synthetic Strategies for the Glycodendrimers
   17. Common Rearrangement Reactions in carbohydrate chemistry
   18. Synthesis of carbohydrate scaffolds using Tandem (Domino) Reactions