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Methodology for Genetic Studies of Twins and Families

  • Livre Relié
  • 496 Nombre de pages
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Based on NATO NFWO and NIMH Funded Workshops taught in Leuven, Belgium (1987, 1989, and 1991) and Boulder, Colorado, U.S.A. (1990)... Lire la suite
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Description

Based on NATO NFWO and NIMH Funded Workshops taught in Leuven, Belgium (1987, 1989, and 1991) and Boulder, Colorado, U.S.A. (1990).

Texte du rabat

Few would dispute the truth of the statement `People are Different', but there is much controversy over emwhy./em This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. br/ The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears. br/



Contenu

Preface. List of Figures. List of Tables. 1. The Scope of Genetic Analyses. 2. Data Summary. 3. Biometrical Genetics. 4. Matrix Algebra. 5. Path Analysis and Structural Equations. 6. LISREL Models and Methods. 7. Model Fitting Functions and Optimization. 8. Univariate Analysis. 9. Power and Sample Size. 10. Social Interaction. 11. Sex Limitation and GE Interaction. 12. Multivariate Analysis. 13. Direction of Causation. 14. Repeated Measures. 15. Longitudinal Mean Trends. 16. Observer Ratings. 17. Assortment and Cultural Transmission. 18. Future Directions. Appendices: A. List of Participants. B. The Greek Alphabet. C. LISREL Scripts for Univariate Models. D. LISREL Script for Power Calculation. E. LISREL Scripts for Multivariate Models. F. LISREL Script for Sibling Interaction Model. G. LISREL Scripts for Sex and GE Interaction. H. LISREL Script for Rater Bias Model. I. LISREL Scripts for Direction of Causation. J. LISREL Script and Data for Simplex Model. K. LISREL Scripts for Assortment Models. Bibliography. Index.

Informations sur le produit

Titre: Methodology for Genetic Studies of Twins and Families
Auteur:
Code EAN: 9780792318743
ISBN: 978-0-7923-1874-3
Format: Livre Relié
Genre: Médecine
nombre de pages: 496
Poids: 947g
Taille: H33mm x B235mm x T155mm
Année: 1992
Auflage: 1992.

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