For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.

The book is a unique combination of data obtained in field studies and laboratory investigations of the various types of molecular adaptations to extreme environments The book presents results of data accumulated over almost 30 years of studies of various animals inhabiting highly aggressive niches The book represents the first attempt to investigate the role of stress proteins on whole body adaptations to adverse conditions

Contenu
Introduction.- The discovery of heat shock response system and major groups of heat shock proteins.- Molecular functions of heat shock proteins.- Regulation of heat shock genes expression.- Heat shock proteins and adaptation to variable and extreme environments.- Different trends in the evolution of heat shock genes systems.- The role of mobile elements in the evolution and function of Hsps systems.- Fine tuning of the HSR in various organisms.- Experimental modulation of heat shock response.- Glossary.