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MHC Volume 2

  • Couverture cartonnée
  • 254 Nombre de pages
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Zusatztext Ein Praxisbuch für Pro/ENGINEER-Anwender und -Lernende. Anhand von Beispielenaus dem Maschinen- und Fahrzeugbau wi... Lire la suite
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Zusatztext Ein Praxisbuch für Pro/ENGINEER-Anwender und -Lernende. Anhand von Beispielenaus dem Maschinen- und Fahrzeugbau wird das Konstruieren und Berechnenanschaulich erläutert. Informationen zum Autor Dr Nelson Fernandez, Dept of Biological and Chemical Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK. Tel: 01206 873330. Fax: 01206 872592. Email: nelson@essex.ac.ukDr Geoff Butcher, Babraham Institute, Babraham, Cambridge, UK Klappentext MHC2: A Practical Approach offers a comprehensive and accessible guide to the fast-growing and fascinating field of MHC research. This companion volume to MHC1 covers topics including: generation of HLA-specific human monoclonal antibodies; sequencing of proteins; assembly of MHC molecules; expression, purification, and characterization of recombinant soluble MHC class I molecules; mapping the human MHC; derivation and analysis of MHC transgenic mice; cell-surface MHC antigen imaging; sequence analysis of MHC molecules; and techniques to identify the rules governing class II MHC-peptide interaction. This informative guide will be an invaluable aid to clinicians, researchers, and graduate students in the field of immunology. Zusammenfassung The major histocompatibility complex is the subject of much research in the immunology area. There is interest in the structure of MHC proteins and in their function as antigen-presenting molecules. This volume provides an introduction to this subject. Inhaltsverzeichnis 1. Generation of HLA-specific human monoclonal antibodies; 2. Sequencing of proteins isolated by one or two dimensional gel electrophoresis; 3. Assembly of MHC molecules: requirements of glycosylation, oxidized glutathione, and peptides; 4. Expression, purification, and characterization of recombinant soluble MHC class I molecules; 5. The use of pulsed field gel electrophoresis to map the human MHC; 6. Derivation and analysis of MHC transgenic mice; 7. Imaging of individual cell surface MHC antigens using fluorescent particles; 8. Sequence analysis of major histocompatibility molecules; 9. Approaches to studying MHC expression in mammals other than primates; 10. Techniques to identify the rules governing class II MHC-peptide formation ...

Informations sur le produit

Titre: MHC Volume 2
Sous-titre: A Practical Approach
Éditeur:
Code EAN: 9780199635559
ISBN: 978-0-19-963555-9
Format: Couverture cartonnée
Editeur: Oxford University Press
Genre: Médecine
nombre de pages: 254
Poids: 446g
Taille: H235mm x B157mm x T15mm
Année: 1998

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