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Methods of Behavior Analysis in Neuroscience

  • Livre Relié
  • 360 Nombre de pages
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Presents various behavioral approaches in animal subjects. This book features material on the relevance of transgenic mouse models... Lire la suite
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Description

Presents various behavioral approaches in animal subjects. This book features material on the relevance of transgenic mouse models for Alzheimer's disease. It discusses behavioral methods for assessing the cognitive impairment associated with major psychotic disorders.

Auteur

Medical College of Georgia, Augusta, USA

Texte du rabat

<P>A comprehensive reference for the most well-studied behavioral approaches in animal subjects, this book provides a better understanding of disease effects and new therapeutic treatments. The second edition features new material on the relevance of transgenic mouse models for Alzheimer's disease, behavioral methods for assessing the cognitive impairment associated with major psychotic disorders, the revival of the scopolamine reversal model for assessing the clinical relevance of new AD drugs, and new approaches to assessing cognitive impairment in aged mice. Each chapter presents theoretical background, methodology, and data interpretation.</P>

Résumé

Behavioral techniques used in animals to model human diseases and predict effects of novel drugs are as varied as the numbers of scientists who use them. Consequently, behavioral analysis is becoming an increasingly indispensable tool for the neuroscientist as information gained at the molecular and cellular level is put into practice in fully behaving animal subjects.

Uses Animal Behavior Models to Examine Effects of Therapeutic Treatments on Human Cognition

With contributions from more than 40 field specialists, Methods of Behavioral Analysis in Neuroscience reflects six years worth of updates to its first bestselling edition and elucidates new behavioral approaches that are quickly becoming field standards. This edition features new material on the relevance of transgenic mouse models for Alzheimer's disease, behavioral methods for assessing the cognitive impairment associated with major psychotic disorders, the revival of the scopolamine reversal model for assessing the clinical relevance of AD drugs, and approaches to assessing cognitive impairment in aged mice.

Each chapter presents theoretical background, methodology, and data interpretation, and many chapters include real-world examples of experiments that incorporate the models. With step-by-step, easy-to-reproduce methodologies, this sharply focused work covers well-studied behavioral approaches that provide a better understanding of the effects of disease and allow for better predictability of the effects of therapeutic treatments on the human cognition. It takes the guesswork out of designing the methodology for many of the most widely used animal behavioral approaches developed for the study of brain disorders, drug abuse, toxicology, and cognitive drug development.



Contenu

Transgenic Mouse Models of Alzheimer's Disease: Behavioral Testing and Considerations, K.J. Bryan, H. Lee, G. Perry, M.A. Smith, and G. Casadesus

Cued and Contextual Fear Conditioning for Rodents, P. Curzon, N.R. Rustay, and K.E. Browman

Drug Discrimination, R. Young

Conditioned Place Preference, A.J. Prus, J.R. James, and J.A. Rosecrans

Anxiety-Related Behaviors in Mice, K.R. Bailey and J.N. Crawley

Behavioral Assessment of Antidepressant Activity in Rodents, V. Castagne, P. Moser, and R.D. Porsolt

Assessing Attention in Rodents, P.J. Bushnell and B.J. Strupp

The Behavioral Assessment of Sensorimotor Processes in the Mouse: Acoustic Startle, Sensory Gating, Locomotor Activity, Rotarod, and Beam Walking, P. Curzon, M. Zhang, R.J. Radek, and G.B. Fox

Intravenous Drug Self-Administration in Nonhuman Primates, L.L. Howell and W.E. Fantegrossi

Contextually Induced Drug Seeking During Protracted Abstinence in Rats, J.J. Buccafusco and L. Shuster

Operant Analysis of Fronto-striatal Function in Rodents, M.D. Dobrossy, S. Brooks, R. Trueman, P.J. Brasted, and S.B. Dunnett

Working Memory: Delayed Response Tasks in Monkeys, J.S. Rodriguez and M.G. Paule

Spatial Navigation (Water Maze) Tasks, A.V. Terry, Jr.

Water Maze Tasks in Mice: Special Reference to Alzheimer's Transgenic Mice, D. Morgan

Behavioral Neuroscience of Zebrafish, E.D. Levin and D.T. Cerutti

Caenorhabditis elegans Model for Initial Screening and Mechanistic Evaluation of Potential New Drugs for Aging and Alzheimer's Disease, Y. Luo, Y. Wu, M. Brown, and C.D. Link

The Revival of Scopolamine Reversal for the Assessment of Cognition-Enhancing Drugs, J.J. Buccafusco

Index

Informations sur le produit

Titre: Methods of Behavior Analysis in Neuroscience
Éditeur:
Code EAN: 9781420052343
ISBN: 978-1-4200-5234-3
Format: Livre Relié
Editeur: Taylor and Francis
Genre: Biologie
nombre de pages: 360
Poids: 635g
Taille: H234mm x B156mm
Année: 2008
Auflage: 2. A.

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