Metal Carbenes in Organic Synthesis

Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportunities in carbon carbon bond formation based on either carbene-centered reactions or on metal-templated processes which makes them indispensable in modern synthetic methodology. The most prominent metal carbenes are now either commercially available or easy to synthesize and handle by modern laboratory techniques. This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background, non-classical nucleophilic and cycloaddition patterns, chromium-templated benzannulation and photo-induced reactions, rhodium-catalyzed carbene transfer as well as the principles and applications of olefin metathesis which coined the progress in synthetic methodology over the past decade. Designed for researchers in academia and industry as well as graduate students it presents the state-of-the-art potential of carbene complexes in modern organic synthesis.

Each volume of Topics in Organometallic Chemistry provides the broad scientific readership with comprehensive summary and critical overview of a topic in organometallic chemistry Research in this rapidly developing transdisciplinary field is having profound influence on other areas of scientific investigation, ranging from catalytic organic synthesis to biology, medicine and material science

Contenu
T. Strassner: Electronic Structure and Reactivity of Metal Carbenes.- Y.-T. Wu, A. de Meijere: The Multifaceted Chemistry of Variously Substituted a,b-Unsaturated Fischer Metalcarbenes.- J. Barluenga, F. Rodríguez, F.J. Fañanás and J. Flórez: Cycloaddition Reactions of Group 6 Fischer Carbene Complexes.- A. Minatti, K.H. Dötz: Chromium-Templated Benzannulation Reactions.- L.S. Hegedus: Photoinduced Reactions of Metal Carbenes in Organic Synthesis.- M.P. Doyle: Metal Carbene Reactions from Dirhodium(II) Catalysts.- B. Schmidt, J. Hermanns: Olefin Metathesis Directed to Organic Synthesis: Principles and Applications.- J. Mulzer, E. Öhler: Diene, Enyne and Diyne Metathesis in Natural Product Synthesis