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Modeling Cellular Signaling Systems

  • Couverture cartonnée
  • 128 Nombre de pages
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At the cellular level, theorize about the molecular mechanisms of cells to communicate with the environment implies to take into c... Lire la suite
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Description

At the cellular level, theorize about the molecular mechanisms of cells to communicate with the environment implies to take into consideration concurrent processes, elements, and relationships that define the functionality of cells over time. The cell-membrane, the surface that acts as a boundary contains many receptors which are responsible for interacting with diverse signaling molecules and recognize external information that affects the behavior in a cell. Each receptor detects specific molecules that may bind to it, which activates signaling pathways that regulate molecular mechanisms, the flow and the processing of biochemical information. There is a special class of receptors that constitutes a common target of pharmaceutical drugs, the G protein-coupled receptors (GPCRs). These receptors interact with their respective Guanine nucleotide-binding proteins (G Proteins) to induce an intracellular signaling. In this thesis we study, in a compositional way, interesting biological scenarios in the context of signaling biochemical networks by using the nTCC calculus, a non-deterministic temporal extension of Concurrent Constraint Programming (CCP).

Auteur

Graduated with an honors master degree in Computer Science. With a Bachelor Science degree in Molecular Biology and in Science, Technology and Society. Interested to understand the integration and the interactions of the components in biological systems. A scientist and humanist, who thinks about the complexity and the expression of life.

Informations sur le produit

Titre: Modeling Cellular Signaling Systems
Auteur:
Code EAN: 9783846537565
ISBN: 978-3-8465-3756-5
Format: Couverture cartonnée
Genre: Informatique
nombre de pages: 128
Poids: 209g
Taille: H220mm x B150mm x T8mm
Année: 2011
Auflage: Aufl.