Cancer Chemotherapy 1

Where do you begin to look for a recent, authoritative article on the diagnosis or management ofa particular malignancy? The few general onco logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can nev er be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by div iding the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Contenu

1. Relevance of drug resistance in cancer treatment strategy.- 2. Animal models for drug scheduling.- 3. Animal models for cancer chemotherapy.- 4. The human tumor cloning assay: An in vitro assay for antitumor activity in solid tumors.- 5. The anthracycline antibiotics: New directions in drug development and cancer treatment.- 6. Cisplatin in cancer therapy: Optimization of treatment regimens and toxicity protection.- 7. Platinum analogues: Criteria for selection.- 8. Chemotherapy based on amino acid depletion and amino acid antagonists.- 9. Chemotherapy of testicular cancer: From palliation to cure.- 10. The impact of chemotherapy on the treatment of gastric cancer.- 11. Therapy of acute myelogenous leukemia.