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Predictors in rectal cancer patients

  • Couverture cartonnée
  • 76 Nombre de pages
With improved surgical techniques and preoperative radiotherapy (RT) the local recurrence rate in rectal cancer patients has been ... Lire la suite
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Description

With improved surgical techniques and preoperative radiotherapy (RT) the local recurrence rate in rectal cancer patients has been reduced, however the mortality rate is still high and there is a huge variation in the response to preoperative RT in patients with the same tumour stage. To improve patient s survival, it is of great importance to identify good prognostic and predictive factors that help us to select the best suited patients for preoperative RT in the future. In this thesis, we wanted to investigate the biological factors, survivin and PINCH, and the histological factors, inflammatory infiltration, fibrosis, necrosis, mucinous content, angiogenesis and lymphangiogenesis. Further we wanted to investigate these biological and histological factors in relation to preoperative RT and to clinical variables in rectal cancer patients participating in a clinical trial of preoperative RT.

Auteur

Annica E. Holmqvist, MD. PhD: Studied medicine at the University Hospital of Linköping and finished PhD studies in March 2011. Work as a Medical doctor and with colorectal cancer research at the University Hospital of Linköping.

Informations sur le produit

Titre: Predictors in rectal cancer patients
Auteur:
Code EAN: 9783848424139
ISBN: 978-3-8484-2413-9
Format: Couverture cartonnée
Genre: Médecine
nombre de pages: 76
Poids: g
Taille: H220mm x B220mm
Année: 2012
Auflage: Aufl.

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